By Step 4 which will take place no earlier than 21 June, the UK government hopes to be in a position to remove all legal limits on social contact. We hope to reopen remaining premises, including nightclubs, and ease the restrictions on large events and performances that apply in Step 3.
Prague COVID-19 Response – July 2020:
“Those who cannot remember the past are condemned to repeat it”
“Here we report the discovery of 24 recent B.1.1.482 pango lineage SARS-CoV-2 viruses in South Yorkshire that have acquired approximately 23 additional mutations when compared to the majority of other samples of this lineage. Nine of these additional mutations are found in the spike gene and six represent changes which are found in variants of interest and concern across the world and/or associated with reduced antibody binding (T95I, G142D, △144, N439K, E484K, P681H). Similar mutation profiles were also seen in B.1.1.482 samples from other regions in the UK. We recommended the monitoring of samples of this lineage which is now designated AV.1.”
Virological.org – Detection of Spike Mutations; D80G, T95I, G142D, △144, N439K, E484K, P681H, I1130V, and D1139H, in B.1.1.482 Lineage (AV.1) Samples from South Yorkshire, UK (UK Variant under investigation VUI-21MAY-01)
Public Health England has revealed that it had detected another Covid variant in Yorkshire and the Humber which it has assigned as a ‘Variant Under Investigation’ VUI-21MAY-01. The strain, temporarily named AV.1, has been spotted 49 times so far.
New Variant Under Investigation
“A further variant, VUI-21MAY-01, has been designated as a Variant Under Investigation (VUI) by PHE.
The variant is from a lineage which was designated a signal in monitoring on 6 May 2021 based on an unusual mutation profile. PHE has been monitoring the variant since April.
There have been 49 cases of VUI-21MAY-01 across the country to date, mainly concentrated in Yorkshire and the Humber.
There is currently no evidence that this variant causes more severe disease or renders the vaccines currently deployed any less effective. PHE is carrying out increased laboratory testing to better understand the impact of the mutations on the behaviour of the virus.”