Lancet: Patients co-infected with intestinal parasites had lower odds of developing severe COVID-19

751 SARS-CoV-2 infected patients with intestinal parasitic infection were enrolled. Patients co-infected with parasites had lower odds of developing severe COVID-19.

Only 27/255 (10.6%) severe COVID-19 patients were co-infected with intestinal parasites, while 257/496 (51.8%) non-severe COVID-19 patients were parasite positive (p<0.0001). Patients co-infected with parasites had lower odds of developing severe COVID-19, with an adjusted odds ratio (aOR) of 0.23 (95% CI 0.17–0.30; p<0.0001) for all parasites, aOR 0.37 ([95% CI 0.26–0.51]; p<0.0001) for protozoa, and aOR 0.26 ([95% CI 0.19–0.35]; p<0.0001) for helminths.

Interpretation: Parasite co-infection is associated with a reduced risk of severe COVID-19 in African patients. Parasite-driven immunomodulatory responses may mute hyper-inflammation associated with severe COVID-19.

Lancet paper: Effect of co-infection with intestinal parasites on COVID-19 severity: A prospective observational cohort study

 

Just please, don’t try this at home folks!

 

 

 

 

Image of Trichuris trichiura by By Daniel J. Drew – https://www.gbif.org/occurrence/1571554104, CC0, https://commons.wikimedia.org/w/index.php?curid=86159945

Ethiopia: man survives triple coinfection of Covid-19, HIV, and tuberculosis

A 55-year-old male arrived at the hospital with HIV, Covid-19 and tuberculosis. On June 6, 2021, the patient recovered and was discharged after 10 days in hospital

This case report suggests, after 10 days of admission with triple infections, there is a good clinical prognosis and survival from COVID-19. On admission, further diagnosis and investigations of TB coinfection should be performed for all patients admitted with COVID-19 due to their similar and non-specific clinical manifestations.

Dovepress.com case report

 

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