Israel: “85-90% of the hospitalizations are in fully vaccinated people”

Dr Kobi Haviv, Herzog Hospital, Jerusalem: “95% of the severe patients are vaccinated”. “85-90% of the hospitalizations are in fully vaccinated people.” “The effectiveness of the vaccine is waning/fading out”


So what is Plan B if the vaccines fail with a new coronavirus super-variant?



Israel: National lockdown if booster jabs don’t work

An official in the high-level coronavirus cabinet, speaking on the condition of anonymity, tells the Kan public broadcaster that the government will wait and see what the effects of the third vaccine booster shot are before declaring a nationwide lockdown.

“The chances of a lockdown in August are slim,” the official says. “The assessment is that they’ll wait two weeks to see if the third shot helps bring down serious cases among the over 60s and if we see a wave of vaccinations among teenagers. If that doesn’t happen, the question is not if there will be a lockdown, but when.” report


Booster jabs may be extended to younger Israelis

At the last Corona Cabinet meeting on Tuesday night, Prime Minister Naftali Bennett raised the possibility that Israel would soon advance to a 40-60-year-old vaccine with third impulse injections – but the head of public health services at the Ministry of Health, Dr. Sharon Elrai Price, reacted and cooled Bennett’s initiative report




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USA, Maryland: “I went to a party with 14 other vaccinated people; 11 of us got COVID”

I’m an epidemiologist at a major medical research university.  I had gone to a house party in Montgomery County. There were 15 adults there, all of us fully vaccinated. The next day, our host started to feel sick. The day after that, she tested positive for COVID-19. At this point, 11 of the 15 have tested positive for COVID.

Baltimore Sun report



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Shi Zhengli: We need to learn to live with the virus

Shi Zhengli, China’s ‘Bat Woman’, has said that new variants of Sars-Cov-2 will continue to emerge, but that vaccines are ‘effective’.  “We shouldn’t panic, but we need to prepare to co-exist with the virus in the long term,” Shi told media on Wednesday. report



Bangladesh: the unvaccinated aren’t allowed on the streets

The Bangladeshi government will not allow any unvaccinated people aged 18 or above on the streets from August 11, the day it will relax the ongoing lockdown.  “Anyone above 18 years will not be allowed on streets and on any mode of transport unless they are vaccinated,” Liberation War Affairs Minister AKM Mozammel Haque, who presided over the meeting, told reporters.

The report



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Preprint: C.37 Lambda variant exhibits higher infectivity and immune resistance

“In this study, we demonstrated that three mutations, the RSYLTPGD246-253N, L452Q and F490S mutations, respectively confer resistance to the vaccine-induced antiviral immunity. Additionally, the T76I and L452Q mutations contribute to enhanced viral infectivity. Our data suggest that there are at least two virological features on the Lambda variant: increasing viral infectivity (by the T76I and L452Q mutations) and exhibiting resistance to antiviral immunity (by the RSYLTPGD246-253N, L452Q and F490S mutations).”

BiorXiv preprint: SARS-CoV-2 Lambda variant exhibits higher infectivity and immune resistance



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China: Sars-CoV-2 returns to Wuhan

Authorities in the Chinese city of Wuhan will begin testing its entire population, after a handful of positive coronavirus cases were detected there.  Wuhan has recorded seven locally transmitted cases – the first local infections in more than a year. report


Authorities in Wuhan on Tuesday said they would test its entire population for Covid-19 after the central Chinese city where the coronavirus emerged reported its first local infections in more than a year.  Authorities announced on Monday that seven locally transmitted infections had been found among migrant workers in the city, breaking a year-long streak without domestic cases after it squashed an initial outbreak with an unprecedented lockdown in early 2020.




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USA: Sars-CoV-2 association with PM2.5 particles during wildfire smoke events

We found that a 10 µg/m3 increase in the 7-day average PM2.5 concentration was associated with a 6.3% relative increase in the SARS-CoV-2 test positivity rate, with a 95% confidence interval (CI) of 2.5 to 10.3%. This corresponded to an estimated 17.7% (CI: 14.4–20.1%) increase in the number of cases during the time period most affected by wildfire smoke, from 16 Aug to 10 Oct 2020. article



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Japan: Covid-19 hospitalizations could be limited to severe cases

Hospitalizations in areas of Japan with many coronavirus infections could in principle be limited to patients with severe symptoms and those at high risk of developing them, while people not hospitalized would basically be required to recover at home, the Japanese Ministry of Health, Labor and Welfare announced on Aug. 2.

People admitted to hotels for recuperation would be limited only to people who are thought to have circumstances that suggest they could spread the coronavirus with others at home.

The Mainichi report


Prime Minister Yoshihide Suga decided that only patients with severe cases of COVID-19 can be admitted to hospital, making a policy U-turn. The government had previously said that all patients except for those with mild coughing symptoms should be hospitalized in principle.

Japan reported 12,017 new coronavirus cases Tuesday, the second highest on record



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UK: 5% of children hospitalized with Covid-19 develop brain or nerve complications

A new UK study has found that around 1 in 20 of children hospitalised with COVID-19 develop brain or nerve complications linked to the viral infection. The research, published in The Lancet Child and Adolescent Health and led by the University of Liverpool, identifies a wide spectrum of neurological complications in children and suggests they may be more common than in adults admitted with COVID-19. report


Kirsty Allsopp: We have to learn to live with Covid

Image by Engin Akyurt from Pixabay

Deepti Gurdasani: “This is a virus that we need to eliminate”, condemns “herd immunity” policies

“There’s no country that has attained herd immunity to SARS-CoV-2. And, certainly, there are countries with different levels of vaccination. I mean, some countries have over 60 percent of their population fully vaccinated. There are also countries that have had natural exposure to the infection at very high rates. But it hasn’t extinguished the pandemic. We’ve always seen surges even after that. And I think that reflects several factors.

One, I think natural immunity can wane over time. And I think the durability of that immunity does depend on the severity of original infection. When infections are mild and asymptomatic, we can have at least weighting of neutralizing antibodies and how that correlates with waning immunity. We don’t know yet, but we know that re-infection, or the getting infected again with the virus, either the same variant or another variant, are far more common than we originally thought. Although there is protection, even over longer duration of time, it’s not absolute.” interview with Dr. Deepti Gurdasani **


** One of just a handful of people on Earth who seems to understand the existential threat that Sars-CoV-2  poses


USA: Alabama’s Covid hospitalizations jump by 30% in one night

A report from the Alabama Department of Health’s online dashboard showed 1,883 hospitalized COVID patients, up by 432 over Sunday’s total. That’s an increase of 29.8% in just one day. The total is the highest since Feb. 1, which was during the downward trend of the winter surge in the virus, just as vaccines were first distributed. The pandemic record of 3,084 inpatients was set on Jan. 11. The new total is 11.3 times the low set on June 20 of 166 hospitalized COVID patients and 75% higher than one week ago. report



Hospitals in Texas are also swamped with Covid patients




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Dominic Minghella on “Learning to live with Covid”

This  👆  👆  👆


Github: AY.3.1 – a new sub-lineage of AY.3 concentrated in Mississippi, USA

AY.3 is the main variant being sequenced weekly in Mississippi (>70% of all recent sequences), most falling within this sub-lineage of AY.3 that is distinguished by the mutations described below (>60% of all recent sequences). For example, of 91 Pangolin-typeable sequences generated on 13 July 2021 by Dr. Robinson’s team, from broad sampling across Mississippi, 68 are AY.3 and 13 are unclassified B.1.617.2. Of those 81 Delta sequences, 60 are this new sub-lineage (those sequences are not yet in GISAID and are thus not included in the counts above for the USA or MS). Thus, there is clear epidemiological relevance of this sub-lineage in a region of the USA.

Github: A new sub-lineage of AY.3 concentrated in Mississippi, US


USA: AY.3 genomes increasing faster than Delta B.1.617.2


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