Denmark: 715 Covid deaths in the double and triple vaccinated, 607,000 breakthrough infections

From a vaccinated population of around 4.7 million people, 715 double and triple vaccinated individuals have died of Covid-19 in Denmark. There were a further 326 deaths in people with a single dose of vaccine, making a total of 1,041 breakthrough deaths.

434,803 people who have received two doses of vaccine have had breakthrough Covid infections, and 105,271 people with booster doses have also had a breakthrough infection. A further 67,749 infections in people with a single dose of vaccine, making a total of 607,823 breakthrough infections.

Breakthrough infections seem to be running at about 150,000 a week in Denmark.

 

 

 

Denmark’s SSI Breakthrough infections and vaccine efficacy report (In English and Danish)

SSI Webpage (in English)

 

Denmark: About 75% of Covid hospitalizations are fully vaccinated *13 UPDATES*

Israel: 4th vaccine dose recommended for all adults

A panel of health experts advising the Israeli cabinet on the fight against the coronavirus pandemic has recommended that a 4th vaccine dose be administered to the population over the age of 18 if at least five months passed since receiving the third jab.

Ynetnews.com report

 

 

Israel: Fourth dose of vaccine gives limited protection against Omicron infection

 

 

 

Photo by Towfiqu barbhuiya on Unsplash

Norway: 248 deaths and nearly 52,000 reports of other Covid vaccine side-effects

From a population of just 5.3 million people, Norway has reported a total of 248 deaths as suspected side effects after a Covid vaccine, according to the latest Adverse Reaction Report from the Norwegian Medicines Agency, published on Thursday, 20th January.

The reported deaths are distributed as follows: 227 after the Pfizer vaccine, 15 after Moderna and six after the AstraZeneca vaccine.

The Norwegian Medicines Agency has also received 51,985 reports of suspected side effects. Of these, 26,413 messages have been processed. 4766 are classified as serious and 21,647 are classified as not serious. This means that 18 per cent of the messages that have been processed are classified as serious.

Dagbladet.no report (in Norwegian)

Norwegian Medicines Agency, Adverse Reaction Report (in Norwegian)

 

Around 4.3 million people have been fully vaccinated in Norway

 

Norway has recorded just 1,414 deaths from Covid-19 as of January 21st 2022:

Norway Covid deaths at OurworldinData.org

 

BMJ: We must have raw data for Covid-19 vaccines and treatments now

 

 

Photo by Sunguk Kim on Unsplash

BMJ: We must have raw data for Covid-19 vaccines and treatments now

“despite the global rollout of Covid-19 vaccines and treatments, the anonymised participant level data underlying the trials for these new products remain inaccessible to doctors, researchers, and the public—and are likely to remain that way for years to come. This is morally indefensible for all trials, but especially for those involving major public health interventions.”

British Medical Journal editorial: Covid-19 vaccines and treatments: we must have raw data, now

 

 

Science Magazine: Covid vaccines may cause Long Covid–like symptoms

 

 

Photo by CDC on Unsplash

Science Magazine: Covid vaccines may cause Long Covid–like symptoms

In November 2021, in the New England Journal of Medicine, William Murphy, an immunologist at the University of California, Davis proposed that an autoimmune mechanism triggered by the SARS-CoV-2 spike protein might explain both Long Covid symptoms and some rare vaccine side effects.

Evidence from animal studies supports the idea that antibodies targeting the SARS-CoV-2 spike protein might cause collateral damage, notes Harald Prüss, a neurologist at the German Center for Neurodegenerative Diseases (DZNE) and the Charité University Hospital in Berlin. In 2020, while hunting for antibody therapies for COVID-19, he and his colleagues discovered that of 18 antibodies they identified with potent effects against SARS-CoV-2, four also targeted healthy tissues in mice—a sign they could trigger autoimmune problems.

Science Magazine article

New England Journal of Medicine article:A Possible Role for Anti-idiotype Antibodies in SARS-CoV-2 Infection and Vaccination

Harald Prüss: Do cross-reactive antibodies cause neuropathology in COVID-19?

 

 

 

Image by Engin Akyurt from Pixabay

Italy: 385 Covid deaths and 188,000 new cases in one day despite the harshest restrictions on Earth

Where did it all go wrong for Italy? The pandemic got off to a hideous start in Bergamo, Northern Italy, in 2020, and the country has since gone from one crisis to another in the pandemic.  Italy is now in the midst of one of the worst Omicron battles in the world, despite compulsory vaccinations, vaccine passports, fines for not being vaccinated, and all the other accoutrements of a dystopian police state.

 

Covid case rates have risen again today to over 188,000 new cases in one day:

 

Covid deaths rates are also still rising as the Omicron wave continues:

 

The Delta variant is still at 17 percent of cases in Italy:

 

Italy: 2 cases of Deltacron reported, but they’re NOT recombinant variants

 

 

Image by Stefano Ferrario from Pixabay

CDC: Prior Covid-19 infection offered better protection than vaccination during Delta wave

CDC: “Before Delta became the predominant variant in June, case rates were higher among persons who survived a previous infection than persons who were vaccinated alone. By early October, persons who survived a previous infection had lower case rates than persons who were vaccinated alone.”

CDC website

 

Surviving a previous Covid infection provided better protection than vaccination against Covid-19 during the Delta wave, US federal health authorities said, citing research showing that both the shots and recovery from the virus provided significant defense.

Wall Street Journal report

 

Czech Republic abandons mandatory Covid vaccination

 

 

Image by Julián Amé from Pixabay

Israel: Fourth dose of vaccine gives limited protection against Omicron infection

Preliminary results from the study conducted at Sheba Medical Center showed that after receiving the fourth shot, participants developed higher coronavirus antibody levels, but they were only partly effective in preventing Omicron infections.

Full story at Ynetnews.com

 

Lead researcher Prof Gili Regev-Yochay said the third dose resulted in “much higher antibodies, neutralization and the antibodies were not just higher in quantity but also in quality” than the second dose – but the fourth vaccine did not show  significant antibody increase.

”Maybe there are a few more antibodies but not much more compared to the third dose,” said Regev-Yochay.

 

 

 

 

 

Image by HeungSoon from Pixabay

UK: Covid-19 infections, hospitalizations and deaths by vaccination status for week 2, 2022

A new report out today by the UK Health and Security Agency gives figures for Covid infections, hospitalizations and deaths by vaccination status for the period in which Omicron became dominant in Britain.

UK Covid Infections:

 

UK Hospitalizations:

UK Covid Deaths:

 

UKHSA Covid-19 vaccine surveillance report for week 2, 2022

 

 

 

Image by truthseeker08 from Pixabay

EMA: Immune system could be overloaded by booster vaccinations

The European Medicines Agency warned this week that repeated booster shots are not a sustainable long-term plan. The EMA pointed out that getting a booster every four months could potentially result in diminishing someone’s immune response. “We should be careful in not overloading the immune system with repeated immunization,” a spokesman said.

 

At 22.40, Booster doses could overload the immune system…

Is some sanity finally breaking out at the top?

 

Is Sars-CoV-2 already targeting the vaccinated?

Will future variants of Sars-Cov-2 tailor themselves to target the vaccinated?  Given that up to 90% of the population of some countries are now fully vaccinated, the question should perhaps be: Why would Sars-CoV-2 NOT target the vaccinated? 

Selective pressure on the virus may mean an increasing drift towards variants that can overcome vaccines, as we are already seeing with Omicron.

There is some evidence in the scientific literature that the global vaccination campaign may have, through selective pressure, encouraged the virus to target the vaccinated.

  • In this Medrxiv preprint, “COVID-19 vaccines dampen genomic diversity of SARS-CoV-2: Unvaccinated patients exhibit more antigenic mutational variance”, the authors state that “This study presents the first known evidence that COVID-19 vaccines are fundamentally restricting the evolutionary and antigenic escape pathways accessible to SARS-CoV-2.”
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  • In this PLOS paper, the authors assert that there is a “risk of rapid evolutionary escape from biomedical interventions targeting evolution”, and “predicted resistance timelines are comparable to those of the decay kinetics of nAbs raised against vaccinal or natural antigens, raising a second potential mechanism for loss of immunity in the population.”
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  • In this Frontiersin.org paper, “Implication of SARS-CoV-2 Immune Escape Spike Variants on Secondary and Vaccine Breakthrough Infections”, the authors state: “The increasing degree of immunity in the human population is inevitably conferring a great deal of selective pressure on the virus that promotes the rise of antibody escape mutants. The emergence of immune escape mutants is perhaps most apparent in chronic COVID-19 patients as documented in multiple reports.”
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  • This UK government paper suggested ways in which Sars-CoV-2 may evolve in future: “Antigenic ‘shift’: Natural recombination events that insert a different spike gene sequence (or partial sequence) from human CoVs MERS-CoV… This would recombine into the ‘body’ of SARS-CoV-2 that is capable of high replication in human cells. The consequence could be a virus that causes disease at a level similar to COVID-19 when it first emerged but against which our current battery of spike glycoprotein-based vaccines would not work.
    .
  • In this Virolyvj paper, the authors say “we speculate that with continued circulation, vaccination and convalescent sera therapy, further positively selected for mutations in the NTD are likely to occur.”

 

Shown below, there certainly seems to be a bias towards infecting the vaccinated in the daily case figures from Denmark’s SSI. Double and triple vaccinated individuals were making up ~90% of all new daily cases recently.

Shown above, from the latest Danish report for vaccine breakthrough infections, it is clear that the vaccinated make up far more of new Covid cases than the unvaccinated.

Shown below, nearly 300,000 cases of Covid are vaccine breakthroughs for those with two doses, and nearly 35,000 cases are breakthrough cases for those with three doses.

 

Clearly, Sars-CoV-2 will become under ever greater selective pressure to infect the vaccinated as the pool of unvaccinated people decreases.  Deliberately targeting the vaccinated cohort may be the only possible way for the virus to survive in future.

Addendum:
You may not feel comfortable with the issues this post deals with, but if you haven’t considered the key question in this post – Could Sars-CoV-2 start targeting the vaccinated? –  then you simply haven’t been paying attention for the last two years.

Selective pressure forcing Sars-CoV-2 to target the vaccinated is not only a possibility, with the Omicron variant, it may have already started.

 

Denmark: ~90% of Omicron cases are double or triple vaccinated *17 UPDATES*

ICU doctor to UK Health Secretary: “I do not want to have a vaccination” *3 UPDATES*

Steve James, a consultant anaesthetist at King’s College Hospital in London who has worked in the ICU since early 2020 treating Covid patients, told UK Health Secretary Sajid Javid why he did not believe in vaccination.

Mr James told the PA news agency he did not believe Covid-19 was causing “very significant problems” for young people, adding that his patients in the ICU had been “extremely overweight” with multiple other co-morbidities.

Independent.co.uk report



UPDATE 1 – 8th January 2022

There is a video of the encounter between Dr Steve Smith and Sajid Javid on Sky News here

Steve James, a consultant anaesthetist who has been treating coronavirus patients since the start of the pandemic, told the health secretary about his displeasure on mandatory vaccinations.

“I’m not happy about that,” he said. “I had COVID at some point, I’ve got antibodies, and I’ve been working on COVID ICU since the beginning.

“I have not had a vaccination, I do not want to have a vaccination. The vaccines are reducing transmission only for about eight weeks for Delta, with Omicron it’s probably less.

“And for that, I would be dismissed if I don’t have a vaccine? The science isn’t strong enough.”

Mr James also revealed another of his colleagues held the same position.

Sky News report



UPDATE 2 -8th January 2022

There is more on this story in a Daily Mail report.

The story was headline news in the Mail for a few hours overnight on the 7th/8th January 2022. By the morning, it had disappeared from the front page completely.



UPDATE 3 – 9th January 2022

The Head of King’s College NHS trust says he may lose 1,000 staff over Covid vaccine mandate. He’s concerned that 10% of 14,000 workers are not fully vaccinated.

Guardian report

 



* * A bureaucrat’s worst nightmare – someone who disagrees with them using facts and personal experience **



 

Israel: Effects of 4th Covid booster dose are good, but not good enough

An Israeli health expert has said that although officials are satisfied with the results reported about the effects of the fourth coronavirus shot, they expected more from the second booster.

“The preliminary results showed a five-fold increase in antibody levels, it’s good news, but it’s not enough, we were hoping for better results,” Director of the Infectious Diseases Unit at Sheba Medical Center Prof. Gili Regev-Yochay told Ynet.

Ynetnews.com report

 

** You cannot fight this Hydra with a single weapon. It requires defence in depth.  It requires a multi-layered approach where vaccines represent one single element of a much larger firewall. **

NY Times – The Swiss Cheese Model of Pandemic Defense

 

Israel: Vaccine passport “has run its course and is no longer relevant”

 

* According to Hesiod, the Hydra was the offspring of Typhon and Echidna. It had poisonous breath and blood so virulent that even its scent was deadly. The Hydra possessed many heads, the exact number of which varies according to the source. Later versions of the Hydra story add a regeneration feature to the monster: for every head chopped off, the Hydra would regrow two heads. Heracles required the assistance of his nephew Iolaus to cut off all of the monster’s heads and burn the neck using a sword and fire (Wikipedia)

 

 

 

Image by krystianwin from Pixabay

UKHSA: Vaccine effectiveness drops to just 40% – 50% ten weeks after booster dose

Two to 4 weeks after a booster dose, vaccine effectiveness ranged from around 65% to 75%, dropping to 55% to 70% at 5 to 9 weeks and 40% to 50% from 10+ weeks after the booster.

 

From the UKHSA web page for Covid variants including Omicron updated 31st December 2021:

“As set out last week, the effectiveness of all vaccines against symptomatic infection continues to be lower in all periods against Omicron compared to Delta. The latest data confirmed that among those who had received 2 doses of AstraZeneca, there was no effect against Omicron from 20 weeks after the second dose. Among those who had received 2 doses of Pfizer or Moderna, effectiveness dropped from around 65 to 70% down to around 10% by 20 weeks after the second dose. Two to 4 weeks after a booster dose, vaccine effectiveness ranged from around 65 to 75%, dropping to 55 to 70% at 5 to 9 weeks and 40 to 50% from 10+ weeks after the booster.”

 

Below is the hospitalization table for Omicron from the latest UKHSA Omicron report:

The chart above shows that 66.4% of those hospitalized for Omicron are double or triple vaccinated, and more than 72% of hospitalizations have had at least one dose of vaccine. Children who are too young to be vaccinated but are hospitalized with Omicron will be included in the figures for the unvaccinated.

 

In the meantime, Nightingale wards are being built near hospitals to cope with the ever-growing influx of casualties from the UK government’s hands-off approach to the Covid pandemic.

 

 

UK.GOV: NHS plans new Nightingale facilities in response to Omicron



** The reason we continue to reproduce this type of information is because we are sick and tired of the defensive sophistry that surrounds every release.

If you are going to ‘shift the paradigm of responsibility’ towards the individual, at least give those individuals the information they need to survive this pandemic in an honest and timely fashion. **



Denmark: 90% of Omicron cases are double or triple vaccinated *14 UPDATES*

 

 

 

Image courtesy of Sludge G, CC BY-SA 2.0, via Wikimedia Commons