#Austria and #Denmark to work with #Israel on future #coronavirus vaccines – EU ‘too slow’

Austria’s chancellor, Sebastian Kurz, described the EU’s vaccination deployment as “too slow” as he announced that his country and Denmark would work with Israel on protecting their citizens against new coronavirus variants.

The move by the two member states to form a vaccine manufacturing partnership comes as the latest figures show that 7.5% of the EU population have received a vaccine dose compared with 52% in Israel and 31% in the UK.

“We must prepare for further mutations and should no longer be dependent solely on the EU in the production of second-generation vaccines,” Kurz said.

Full Guardian Report

 

By Bundesministerium für Europa, Integration und Äusseres – Arbeitsbesuch Israel, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=38585833

Outbreak of South African #coronavirus variant in #Copenhagen, authorities ring doorbells and send texts to residents. #N502YV2

There is an outbreak of a South African coronavirus variant B.1.3.5.1 in the North-West quarter of Copenhagen. All citizens close to the outbreak should be tested at the weekend.

This is the message from health and care mayor Sisse Marie Welling (SF) in a press release sent out by the City of Copenhagen on Friday evening.

“For all intents and purposes, the South African variant must not be allowed to spread in Copenhagen,” is her urgent message.

Berlingske.de report

 

Image by iris Vallejo from Pixabay

SSI: #B117 is now the dominant #coronavirus variant in #Denmark after explosive growth

The proportion of people infected with B.1.1.7 increased from 4% in early January to 45% in the second week of February. And B.1.1.7 now accounts for over 60% of the total infection.

As predicted by mathematical model calculations, B.1.1.7 has now been taken over as the most widespread variant in Denmark. Now, results from a Danish study show that B.1.1.7 also seems to carry a 64% greater risk of hospitalizations (95% safety interval 32-104%).

Due to greater infectivity, the proportion of those infected with the B.1.1.7 variant has been steadily growing and is today dominant in Denmark.

There is good reason to take the virus variant B.1.1.7 seriously. Calculations of the variant made by the expert group for mathematical modeling at the Statens Serum Institut (SSI) have since the turn of the year predicted that an undercurrent of infection with the more infectious variant would take over and drive the epidemic in Denmark during February.

Those predictions have proven to hold true. The proportion of people infected with B.1.1.7 increased from 4% in early January to 45% in the second week of February. And B.1.1.7 now accounts for over 60% of the total infection.

Now, the results of a registry-based study conducted by SSI show that people infected with B.1.1.7 have an estimated increased risk of hospitalization compared to people infected with other SARS-CoV-2 virus variants of 64% (95 safety range 32-104%).

“We do not know the explanation for the fact that B.1.1.7 increases the risk of being admitted. But our figures point in the same direction as several other studies from the UK, which show that B.1.1.7 may have more serious courses, ”says Tyra Grove Krause, Acting Technical Director at SSI.

SSI report

 

 

Denmark’s #SSI: “Even without reopening, the development of virus variant B.1.1.7 #B117 and the opening of 0-4yr class lead to slightly increasing infection rates and new admissions in mid-April”

SSI:  “The expert group has all the way counted on a so-called scenario 0, where you do not open further. And where teachers are tested twice a week with an antigen test.

“Even without reopening, the development of virus variant B.1.1.7 and the opening of 0.-4. class lead to slightly increasing infection rates and new admissions in mid-April, ”says doctor Camilla Holten Møller from the expert group.

If, in addition, all graduation classes are opened, according to the group’s calculations, this will lead to a marked increase in the number of infections and the number of new admissions in mid-April.

The report also includes scenarios for 50% attendance in the graduating classes in primary and lower secondary schools and in the upper secondary and adult educations, as well as an infection-reducing effect by repeated antigen tests of 25% and 50%, respectively.”

Denmark’s SSI Announcement

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Denmark was right to cull mink: “SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization”

“These results suggest that antibody responses induced upon infection or certain antibodies used for treatment might offer insufficient protection against SARS-CoV-2 variants from mink.”

Biorxiv.org preprint study

 

felixd, CC BY-SA 4.0, via Wikimedia Commons

New #coronavirus variant #B1525 with #E484K, #Q677H, #F888L and a similar deletions to #B117

International lineage with variants of biological significance E484K, Q677H, F888L and a similar suite of deletions to B.1.1.7.

Countries reported 2
Countries with sequences 10
Sequence count 102
Countries: Denmark 35,  United Kingdom 32,  Nigeria 12,  United States of America 7,  France 5,  Ghana 4,  Australia 2,  Canada 2,  Jordan 2,  Spain 1

cov-lineages.org report

 

Photo by Jakayla Toney on Unsplash

About 20% of health workers in one Danish hospital vaccinated with the #Astrazeneca vaccine experience mild side effects

The North Jutland Region of Denmark is to vaccinate one third of a hospital ward staff at a time instead of a half. The slowdown is due to more employees reporting in sick after they have been vaccinated with the AstraZeneca vaccine, writes TV2 Nord.

‘Approximately 20 percent of those vaccinated experience mild side effects from the vaccine. There is nothing unusual about that. ”

“A small percentage will also experience side effects that require a few days of sick leave. In that sense, it is also normal, “says Søren Hjortshøj [Hospital].

Also in Sweden, hospital employees have become ill after vaccination with the AstraZeneca vaccine. As a result, two regions have temporarily suspended their use of the vaccine. One region is Sörmland, where about 100 out of 400 vaccinated hospital staff have experienced side effects such as fever.

Berlinske.de report

 

Image by valelopardo from Pixabay

B.1.1.7 Kent #coronavirus variant now at 28% in Denmark

The UK B.1.1.7 variant was detected in 28.5 percent of the samples in Denmark sequenced up to Friday 12th February 2021 from the first week of February 2021.

For comparison: in the week before, the share was still 20.3 percent, at the turn of the year it was only 2.1 percent.

The SSI estimates that B.1.1.7 will probably be the dominant virus variant in the course of February 2021.

SSI Denmark Report

 

Image by Orna Wachman from Pixabay

561 cases of #coronavirus variant B.1.1.7 reported in Denmark

“561 people with this variant have now been detected in Denmark. A total of 7.4% of all sequenced samples in week 2 were found positive for B.1.1.7 compared to 4% of all positive samples in week 1. The proportion of B.1.1.7 cases among sequenced samples varies from approx. 2-10% in different regions highest in Region Zealand and Southern Denmark, lowest in Region North Jutland.”

https://www.ssi.dk/aktuelt/nyheder/2021/yderligere-to-danskere-smittet-med-variant-b-1-351-der-forst-blev-pavist-i-sydafrika

 

Image by Wilfried Pohnke from Pixabay

Denmark: just 3.% of test group had #coronavirus antibodies by November 2020.

At the end of November, 3.9% of study participants had antibodies to neon coronavirus in their blood samples. This means that our best estimate of the proportion of the population that had been infected with covid-19 up to the beginning of December is 3.9%.

The calculation is subject to an uncertainty ranging from 3.3% to 4.6%. This corresponds to between 160,000 and 230,000 people in Denmark in the age group of 12 years and older having been infected with covid-19.

The study shows that the proportion of the population who have antibodies is increasing. The proportion of infected in this round of the study had almost doubled since the last round, which was in mid-August. At that time, 2.1% (with an uncertainty of 1.8% -2.6%) of the participants had antibodies.

https://www.ssi.dk/aktuelt/nyheder/2021/praevalensundersoegelse_19_1_2021

Image by Sharon Ang from Pixabay

Denmark finds 4 #coronavirus cases which only have the E484K mutation in the spike protein

The first case of another covid-19 variant has been found in Denmark. This is the virus variant B.1.351 / 501Y, which was originally detected in South Africa .

The Danish covid-19 case of B.1.351 / 501Y was found on Zealand and is associated with a trip to Dubai. The variant has both the 501Y mutation, which is associated with greater infectivity, and the 484K mutation, which may lead to a decrease in the sensitivity to the protective antibodies in patients who have recovered from COVID-19 infection.

At the same time, the Statens Serum Institut (SSI) has found four covid-19 cases with another virus variant, which only has the E484K mutation in the Spike protein, which as mentioned before may be associated with reduced sensitivity to the protective antibodies.

https://www.ssi.dk/aktuelt/nyheder/2021/det-foerste-tilfalde-af-ny-covid-19-variant-er-nu-fundet-i-danmark

 

 
Image by PublicDomainPictures from Pixabay

New UK #Sarscov2 B117 variant is now 7% of all cases in North Jutland and 2.3% of all cases in Denmark

At Aalborg University, Professor Mads Albertsen heads a research group that has followed the British mutation since it was discovered in December.

“If it is 74 percent more contagious , then we get an infection curve that rises very sharply again, and therefore we get many more dead. It is the horror scenario that it is so much more contagious , because then we get a pandemic, which is very difficult to control”

 

Image by José R Valverde from Pixabay