#School pupil infected with South Africa #coronavirus variant #B1351 in Achberg, Germany. 150 people in quarantine

The school had to close last Friday, just under a week after it opened. The boy’s classmates and teachers and their families are affected by the quarantine. Two kindergarten groups also had to be isolated as a precaution because a sibling of the student was being looked after there. Where the boy was infected is unclear, said a community spokeswoman.

Because the boy’s teacher also tested positive , their contacts and their families also had to be in quarantine. However, it is still unclear whether the infection is a virus mutation.

FAZ.NET report dated 11.55am, 1st March 2021

 

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Recombinant #coronavirus in #Norway combines UK, South Africa and Brazil variants

A multivariant of the British, South African, and Brazilian corona variant has been detected in a sample taken from a person who came to Trondheim from abroad.

There has been no further spread, municipal chief medical officer Tove Røsstad told newspaper Nidaros.

“We were informed of this after the person in question had finished his isolation period. It was a person who came from abroad and who tested positive at the border,” Røsstad noted.

According to Røsstad, the virus sample had some elements from the Brazilian variant, from the British variant, and the South African variant.

Norwaytoday report

 

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South Africa Has Found About 4,000 #Covid19 Reinfections with B.1.351 #B1351 #501YV2

South Africa confirms 4,000 reinfections due to B.1.351

The president of the South African Ministerial Advisory Committee on Vaccines, Barry Schoub, reported this Wednesday that some 4,000 reinfections of coronavirus have already been registered in the country due to the mutation of one of its strains.

Schoub explained that “this is probably largely due to the variant” of the virus that was first identified in South Africa last year, known to scientists as B.1.351, which has become the dominant strain.

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Johnson and Johnson vaccine has a 72% overall efficacy rate in the US and 64% in South Africa

The Johnson and Johnson vaccine had a 72 percent overall efficacy rate in the United States and 64 percent in South Africa, where a highly contagious variant emerged in the fall and is now driving most cases. The efficacy in South Africa was seven percentage points higher than earlier data released by the company.

The vaccine also showed 86 percent efficacy against severe forms of Covid-19 in the United States, and 82 percent against severe disease in South Africa. That means that a vaccinated person has a far lower risk of being hospitalized or dying from Covid-19.

New York Times Report

 

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Moselle, France: “more than a third of coronavirus cases in circulation are of South African origin” #501YV2

The presence of variants in Moselle, France, continues to worry. After his visit last Thursday, Olivier Véran indicated this Tuesday afternoon, during questions to the government at the National Assembly that “more than a third of the cases in circulation are of South African origin”. The department is the “only place in the territory “where such a rate is observed,” said the minister.

According to Isabelle Lux, assistant to the town hall of Metz, contacted by CheckNews “more than 40% of the variants are South African or Brazilian on all the positive results for Sars-Cov-2 in Moselle between the end of the last week and the start of this week”.

Note that the incidence rate of the Moselle has climbed since the end of January to exceed the national average. Between February 6 and 12, it was 281 per 100,000 inhabitants against 189 on average in France.

Liberation.fr report

 

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New #coronavirus variant #B1525 with #E484K, #Q677H, #F888L and a similar deletions to #B117

International lineage with variants of biological significance E484K, Q677H, F888L and a similar suite of deletions to B.1.1.7.

Countries reported 2
Countries with sequences 10
Sequence count 102
Countries: Denmark 35,  United Kingdom 32,  Nigeria 12,  United States of America 7,  France 5,  Ghana 4,  Australia 2,  Canada 2,  Jordan 2,  Spain 1

cov-lineages.org report

 

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The Global #Coronavirus Case Fatality Rate #CFR is now at 2.21% and rising

The global case fatality rate, which fell consistently from May 1st 2020 until January 18th 2021, is now rising steadily and currently stands at 2.21%

The global Covid-19 case rate (those who have tested positive for sars-cov-2 by testing) has fallen recently, but the case fatality rate (those who have died of Covid-19 following a confirmed test) has not fallen in step with the case reduction.

The most obvious conclusion is that the Covid-19 fatality rate is just lagging the case rate by some weeks. Alternatively, the recent bad weather across much of Europe may have affected testing capacity.

There are other possible explanations though:

  • More aggressive Sars-cov-2 variants are leading to an increase in the mortality rate without a corresponding increase in case rates – see here
  • Sars-cov-2 variants may be evading testing?

Case Fatality Rate Chart

WHO: Recovered #coronavirus patients have been reinfected with new virus strains

Preliminary reports from South Africa suggest people with prior Covid infection could be reinfected with a new, more infectious variant of the virus, the World Health Organization said.

Initial findings also show Covid vaccines may be less effective in protecting against new strains of the virus, but vaccination may reduce the severity of infection, WHO said.

Vaccination may also decrease the spread of new Covid variants, according to WHO.

CNBC Report

 

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Circulating SARS-CoV-2 variants B.1.1.7, 501Y.V2, and P.1 have gained ability to utilize rat and mouse Ace2 and altered in vitro sensitivity to neutralizing antibodies and ACE2-Ig

Here, we first investigated cross-species receptor usage of multiple SARS-CoV-2 variants that emerged during the pandemic. We found that, in contrast to an early isolate WHU01, the circulating variants B.1.1.7/501Y.V1, B.1.351/501Y.V2, and P.1/501Y.V3 were able to use rat and mouse Ace2 orthologs as entry receptors, suggesting that rats and mice might be able to harbor and spread these variants.

https://www.biorxiv.org/content/10.1101/2021.01.27.428353v2

 

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Fauci: new #coronavirus variant has caused #reinfection in #SouthAfrica

Fauci: “When we were communicating with our many scientific and public health colleagues in South Africa, they were telling us over the phone ‘something strange is going on right now, we have people who were infected several months ago, who now with this new strain are getting reinfected, which is telling you that the immune response induced to the first infection wasn’t good enough to prevent the second infection”

https://edition.cnn.com/world/live-news/coronavirus-pandemic-vaccine-updates-01-30-21/index.html

 

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Novavax vaccine works well except on N501Y.V2 South Africa variant

An early analysis in Britain found that the Novavax vaccine had an efficacy rate of nearly 90 percent. But in a small South Africa trial, the efficacy rate dropped to just under 50 percent.

https://www.nytimes.com/2021/01/28/health/covid-vaccine-novavax-south-africa.html

 

 
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