Category: Genome
Preprint: Mutated SARS-CoV-2 variant resistant to remdesivir
A new preprint study shows that two kidney transplant patients treated with immunosuppressive drugs, and who later had a lengthy COVID-19 infection, developed a version of the virus with a genetic change that made it resistant to the antiviral therapy remdesivir.… ...More...
BA.2.75.2 and BQ.1.1 approaching SARS-1 levels of escape
A new Twitter thread out today from Yunlong Cao gives further details about the variants BA.2.75 and BQ.1.1.… ...More...
Preprint: Russian Khosta-2 bat virus resistant to SARS-CoV-2 vaccines
“We found that the spike from virus, Khosta-2, could infect cells similar to human pathogens using the same entry mechanisms, but was resistant to neutralization by serum from individuals who had been vaccinated for SARS-CoV-2.”… ...More...
BA.2.75.2 “exhibits more extreme antibody escape than any variant we’ve seen so far”
Two preprints have been published over the last few days that give more details about the Omicron BA.2.75.2 sublineage.… ...More...
BA.2.75.2: The “most immune evasive strain we have tested so far”
A Twitter post from Covid researcher Yunlong Cao claims that Omicron BA.2.75.2 is “currently the most immune evasive strain we have tested so far”.… ...More...
WHO: Legionellosis outbreak in Tucuman, Argentina
“Further analyses of two bronchoalveolar lavage samples by highly sensitive total DNA sequencing found readings compatible with Legionella spp.”.… ...More...
Preprint: White-tailed deer still harbouring Alpha, Gamma and Delta variants in New York
Nine lineages including three major variants of concern; Alpha, Gamma and Delta, were detected in White-tailed deer samples in New York.… ...More...
Peru: First South American lineage of monkeypox identified
The health authorities of Peru identified the first South American lineage of the virus that causes monkeypox, which has been designated B.1.6 by the International Scientific Committee “mpxv-lineages”, an official statement reported on Wednesday.… ...More...
Preprint: BA.2.75 centaurus may be much more infective than pre-existing variants
“These results suggest that BA.2.75 can cause more severe respiratory disease than BA.5 and BA.2.”… ...More...
XAY Delta-Omicon recombinant under observation
A new SARS-CoV-2 recombinant lineage from South Africa has been highlighted by Tulio de Oliveira, Director of the Centre for Epidemic Response & Innovation in South Africa today.… ...More...
WHO: BA.2.75 has more efficient replication in lung cells, fusogenicity, pathogenicity
WHO: “Preliminary laboratory-based studies indicate a relative growth advantage of BA.2.75 as compared to BA.2 and BA.5.… ...More...
Monkeypox: 87% of household samples still contaminated after 15 days
Of the 31 environmental swab samples collected by the CDC from the property of a person infected with monkeypox, 87% were still contaminated with the virus after 15 days.… ...More...
Preprint: Potential risk of BA.2.75 to global health is greater than that of BA.5
BA.2.75 spike exhibited a profound higher affinity to human ACE2 than BA.2 and BA.5 spikes.… ...More...
Omicron BA.4.6 at 4 percent of all US sequences
Omicron BA.4.6, a subvariant of BA.4, has been attracting some media attention over the past few days.… ...More...