India: 16% vaccine breakthrough in Delhi hospital #coronavirus study

A small-scale study on 113 healthcare workers who had received at least one vaccine dose at a private hospital in Delhi found that 18 tested positive for Covid but all except one had mild symptoms.  Of the 113 in the study, 107 had received the second dose of the vaccine.

Taken in percentage form, the study found that breakthrough infections — Covid infection in vaccinated individuals — occurred in 15.9 per cent (18 persons) of the vaccinated individuals and 95 per cent had mild symptoms. Of these, 17 incurred the infection after the second dose. According to the study, of the breakthrough infections in 18 persons, 17 incurred the infection after the second dose. These 17 had got their second dose after a mean of 34.8 days following the first jab.

NDTV report

Belgium: Five fully vaccinated care home residents infected with B.1.617.3 in vaccine breakthrough outbreak

Seychelles: 30% #coronavirus vaccine breakthrough rate

Image by shalender kumar from Pixabay

Maldives: 60% positivity rate in Greater Male – “High chance of new #coronavirus variant”

The Maldives Health Protection Agency revealed on Sunday that three out of five samples tested in Greater Male’ Area result in a COVID positive case. Within a two week period, HPA said, the positivity rate at flu clinics have increased by four times.

Maldives is currently in its worst COVID wave to date. With 9,433 active cases, this is the highest the figure has been. Currently, 250 people are hospitalized, Maldives have seen 84 fatalities so far. In February 2020, Maldives started it’s vaccination program, and so far 300,906 people from a population of 531,000 have been given the first dose of the vaccine while 130,886 people have received the second dose.  

 

On average, 80 children below the age of 10 are found to be positive EVERY DAY. This includes 4 to 5 children who are less than a year old.

Edition.mv report

 

Belgium: Five fully vaccinated care home residents infected with B.1.617.3 in vaccine breakthrough outbreak

Five residents of a care home in Borsbeek in Antwerp province have been infected with the so-called Indian variants of Covid-19, according to the Flemish Agency for Health and Care. One of those affected has died.  All of the home’s residents have been fully vaccinated.

In three of the cases involved in the new outbreak, the Indian variant has been confirmed, and it is supposed the same goes for the other two. One has since died, and another is in hospital.

Brussels Times report

 

Image by meineresterampe from Pixabay

Brazil: new #coronavirus strain P.1.2 confirmed circulating in Rio de Janeiro

The State Department of Health of Rio de Janeiro (SES-RJ) announced the identification of the new variant of the Covid virus in Rio de Janeiro late this morning. The strain received the name of P.1.2, because it is a change that occurred in the P.1 line – which appeared in Manaus.

“The objective of the study is to foresee the evaluation of the epidemiological scenario in the state of Rio de Janeiro to anticipate possible genomic alterations of the already known variants and to prepare the state and the municipalities to face any alteration that may change the pattern of the disease”, he affirmed. the superintendent of Epidemiological Surveillance of the Secretary of State for Health, Mário Sérgio Ribeiro.

Also according to the superintendent, still it is not possible to know whether P.1.2 is more lethal or more transmissible . The epidemiological impact is yet to be assessed.

The technical note of the state presents the genomic study with samples carried out between March 24th and April 16th. The study was carried out in partnership between the Lacen-RJ laboratory and the State Department of Health. According to the City Hall of Rio das Ostras, variants P.1 and P.2 have already been confirmed, previously, in the city.

“The presence of these variants in the municipality and the emergence of a new strain reinforce the importance of surveillance and monitoring of virus dispersions, the need to maintain all measures to prevent contagion and to maintain sanitary barriers”, warned the municipality.

Globo.com report

 

Local TV report on Brazilian variant P.1.2 : https://globoplay.globo.com/v/9499613/ (in Brazilian)

 

Brazil: P.1 mutates into new #coronavirus variant P.1.2

 

 

 

Image by Andrea Meakin from Pixabay

USA: 3,084 #coronavirus vaccine breakthrough cases in California

Between Jan. 1 and April 28, California public health officials recorded 3,084 breakthrough cases of COVID-19 in people who were fully vaccinated. That’s out of 12.9 million people who were fully vaccinated.  “As more time passes and more people are fully vaccinated, it is likely that additional post-vaccination cases will occur,” the California Department of Public Health said in a statement. “The number of post-vaccination cases remains small.”

Sacbee.com report

 

Seychelles: 30% #coronavirus vaccine breakthrough rate

 

CDC: 9,245 #coronavirus vaccine breakthough cases in the USA

 

 

Image by Public Co from Pixabay

India: two lionesses at Etawah safari park test positive for #coronavirus

A statement issued by the office of Director of Etawah Safari in Uttar Pradesh, India yesterday stated two lionesses at Etawah safari park have been tested positive for coronavirus and their treatment has begun as advised by experts. It also stated the condition of both animals is normal. Both the lionesses have been down with fever for some time and have been under treatment from vets.

On May 5, authorities of Etawah Safari sent samples of 14 lions and lionesses to IVRI for tests after two of them fell sick.

Indian Express report

 

India: Eight Asiatic Lions test positive for #coronavirus at Hyderabad Zoo

Gamaleya Institute: ‘The next stage of the epidemic is the infection with the #coronavirus of farm and domestic animals’

 

USA: 188 recorded Sars-cov-2 #coronavirus infections in animals including lions, tigers, leopards, mink, cougar, gorillas, cats and dogs

 

Photo by Moe Thet Oo on Unsplash

Brazil: P.1 mutates into new #coronavirus variant P.1.2

A new variant of the Brazilian coronavirus has been identified this week, according to Rio de Janeiro health authorities. The P1 Manaus strain seems to have mutated. Hence, the new version has been named P.1.2., scientists in Rio said.

The new variant P.1.2 was identified in 5.85% of the 376 samples taken in 57 municipalities of the state of Rio, second only to São Paulo in the total number of cases nationwide.

“So far it cannot be said that this variant is more contagious or lethal, which is a mutation of P1,” Rio State Health Undersecretary Claudia Mello said in a statement. She also explained that “the new variant was found mainly in the northern region of the state of Rio de Janeiro, but also the metropolitan area and coastal municipalities.”

MercoPress.com report

 

The new variant of Covid-19 was discovered during an investigation to identify which strains of the virus more circulate in the state. P1 remains in almost all regions and P2 in the north and in the lowlands. 376 samples were investigated, from 57 municipalities, selected from genomes sent to the Noel Nutels Central Laboratory (Lacen / RJ), between March 24th and April 16th.

Olhardigital.com report

 

Brazil: rapid spread and high impact of the #coronavirus VOC P.1 in Sao Paulo – March 2021

 

 

Image by Heiko Behn from Pixabay

UK: Indian #coronavirus variant B.1.617.2 already outcompeting B.1.1.7 in some areas of Britain

UK GOV: “B.1.617.2 has spread rapidly in India based on available data. There have been multiple importations to the UK and onwards transmission within the UK. In some regions, S gene target data suggests that this variant may be more frequent than is indicated by the current sequence data, due to the lag in sequencing, and may have replaced B.1.1.7 to some extent. Modelled growth estimates suggest that the variant is at least as transmissible as B.1.1.7. Further analyses are required with targeted comparator groups and improved correction for importation to refine the position on transmissibility. Some early laboratory data suggest limited antigenic change. There are insufficient data as yet to assess reinfection or vaccine effectiveness through national surveillance.”

UK.GOV: SARS-CoV-2 variants of concern and variants under investigation in England, Technical briefing 10 (PDF download)

 

India: The stunning rise of the B.1.617.2 #coronavirus variant

 

UK: India is added to travel “red list” three weeks too late

 

Image by Free-Photos from Pixabay

UK: surge testing for Indian #coronavirus VOC B.1.617.2 begins in Bolton as some areas see 500% increase in cases

Mobile Covid-19 testing units are being rolled out in Bolton as surge testing gets underway in the borough’s coronavirus hotspots. People in Rumworth, Deane or Great Lever are being urged to get tested at the units. Infection rates in those areas have increased, ­ with Rumworth South seeing cases rocket by 500 per cent, with an infection rate of 359.3 per 100,000 people. In Lever Edge, part of Great Lever, cases have increased by 40 per cent.

Bolton currently has the second highest infection rate in the UK.

The Bolton News Report

 

UK: B.1.617 found in 24% of #coronavirus sequences in Bolton, mostly new VOC B.1.617.2

 

India: The stunning rise of the B.1.617.2 #coronavirus variant

 

Image by David Reed from Pixabay

Nepal: highest-ever number of new #coronavirus cases in last 24 hours at 9,196

Nepal recorded a total of 9,196 new cases of coronavirus infection in the past 24 hours. According to the Ministry of Health and Population, 9,023 persons have been tested positive for COVID-19 through the RT-PCR method while 173 have been tested positive through the Antigen method. According to the Ministry, 3,089 persons in Kathmandu, 643 in Lalitpur, and 374 in Bhaktapur have been tested positive for the pandemic virus, making the capital valley’s fresh coronavirus cases 4,106 in past 24 hours.

According to the Ministry, 50 people have succumbed to COVID-19 related death in past 24 hours taking the death tally to 3,579 as of Friday afternoon.

Kharbahub.com report

Nepal: new #coronavirus daily case rate still closely tied to India’s outbreak

Nepal: rise in #coronavirus cases has similar trajectory to India driven by B117 and B1617

Graph courtesy of OurWorldInData.org

 

France: 40 cases of Breton variant B.1.616 (20C/655Y) with #coronavirus mutations D614G, H655Y, G669S & V482A

As of April 28, 40 cases of infection with the 20C/655Y (B.1.616) variant have been confirmed (37 in Brittany, three in other regions). The diagnosis was made on a first positive RT-PCR from a sample nasopharyngeal in 13% of them, and from a deep sample in 68% of cases. All cases have a direct or indirect link with the enhanced surveillance zone in Brittany. The majority of cases are linked to transmissions within hospital clusters in the area. A few cases have been reported in link with a chain of transmission in the community but, to date, the monitoring indicators do not suggest a significant community diffusion of this variant in the population, whether in Brittany or elsewhere. Epidemiological investigations are continuing to characterize the episode and monitor the diffusion of this variant.

French Health Department Document: COVID-19: epidemiological update of April 29, 2021 (PDF download)

 

France: Breton variant B.1.616 – 37 cases & 16 deaths with just 9% of cases detected by first RT-PCR #coronavirus test

France: 32 cases of Breton #coronavirus variant B.1.616 reported

 

Image by françois zimmermann from Pixabay

UK: B.1.617 found in 24% of #coronavirus sequences in Bolton, mostly new VOC B.1.617.2

Following a rise in cases in the UK and evidence of community transmission, PHE has reclassified B.1.617.2 as a Variant of Concern (VOC). This is based on evidence which suggests this variant, first detected in India, is at least as transmissible as B.1.1.7 (the Kent variant). The other characteristics of this variant are still being investigated.

Cases of B.1.617.2 have increased to 520 from 202 over the last week and almost half the cases are related to travel or contact with a traveller. The cases are spread across the country, however, the majority of the cases are in 2 areas – the North West (predominantly Bolton) and London – and this is where we are seeing the greatest transmission.

PHE Document – Confirmed cases of COVID-19 variants identified in UK

 

India: The stunning rise of the B.1.617.2 #coronavirus variant

 

UK government poised to declare Indian #coronavirus B.1.617 a Variant of Concern or VOC

 

India: double mutant coronavirus variant B.1.617 outcompeting B.1.1.7 UK variant

 

Image by David Mark from Pixabay

India: The stunning rise of the B.1.617.2 #coronavirus variant

Professor Christina Pagel:  [B.1.617] rapidly became dominant in India and, again the sequenced data there is sparse, but early modelling shows that it might well be more transmissible than our B.117 Kent strain. ‘What we have also seen in India is that B.1.617.2 is becoming the dominant subtype – exactly the same pattern we see here in the UK.  ‘While this could reflect the situation in India through importation, the Sanger data tries to exclude travel related cases or surge testing and we still see the rise of B.1.617.2 in that’.

 

WHO: B.1.617 Indian #coronavirus strain is now a Variant of Concern or VOC

UK government poised to declare Indian #coronavirus B.1.617 a Variant of Concern or VOC

 

** NOTE: B.1.617.2 carries the T478K mutation according to the European Centre for Disease Prevention and Control

See also Bioxriv preprint: Preliminary report on SARS-CoV-2 Spike mutation T478K

 

Rapid rise of #coronavirus SARS-CoV-2 spike mutation T478K found in Mexico and several European countries

 

Chart courtesy of Outbreak.info

 

USA: Michigan taxidermist reported infected by mink #coronavirus variant with F486L and N501T mutations

In February 2021, a taxidermist living in Eaton County, Michigan, became infected with COVID-19. A sample from his positive test result was sent to the state lab to be genetically sequenced — and came back as connected to a mutation of the virus found in infected mink, whose fur is used for coats and clothing.

In early February, the linked COVID-19 case involving the Eaton taxidermist was confirmed through genetic testing.

MDHHS confirmed the CDC’s account of the mutations, identifying them as F486L and N501T. Those two mutations have been identified by researchers as the dominant mink COVID-19 strains in the United States, according to a preprint study published last month by two Canadian researchers, and may have evolved in humans before being transmitted to minks,

Freep.com report

 

 

 

Image by Jan den Ouden from Pixabay