Colombia: novel highly divergent #coronavirus SARS-CoV-2 lineage with the Spike substitutions L249S and E484K, assigned to the B.1.111 lineage

Here we report a novel and highly divergent lineage with 21 characteristic mutations, including 10 non-synonymous, 8 synonymous and 3 mutations in non-coding regions (5’and 3’ UTR and intergenic region).

Four Colombian sequences collected between December 26, 2020 and January 14, 2021with a characteristic mutation pattern, including two amino acid changes in the Spike protein (L249S and E484K) were assigned to the B.1.111 lineage

Medrxiv preprint

 

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