Colombia: novel highly divergent coronavirus SARS-CoV-2 lineage with the Spike substitutions L249S and E484K, assigned to the B.1.111 lineage

B.1.111, Colombia, Coronavirus, E484K, Health, Science, Testing, Variants

Here we report a novel and highly divergent lineage with 21 characteristic mutations, including 10 non-synonymous, 8 synonymous and 3 mutations in non-coding regions (5’and 3’ UTR and intergenic region).

Four Colombian sequences collected between December 26, 2020 and January 14, 2021with a characteristic mutation pattern, including two amino acid changes in the Spike protein (L249S and E484K) were assigned to the B.1.111 lineage

Medrxiv preprint


 Image by gustavo9917 from Pixabay

** This post was originally published on April 2, 2021 **