Tag: E484K

Preprint: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2

In this study, we reported the emergence and spread of the novel B.1.621 lineage of SARS-CoV-2, a new VOI with the insertion 146N and several amino acid substitutions in the Spike protein (T95I,Y144T, Y145S, R346K, E484K, N501Y and P681H).  More...

Coronaheadsup.com America, B.1.621, Belgium, Colombia, Coronavirus, E484K, Genome, Infection, Mutation, N501Y, P681H, Science, Testing, Transmission, Vaccine Breakthrough, Y144

Preprint: Persistent coronavirus infection and intra-host evolution in association with advanced HIV infection

“Here we present a case of prolonged infection of greater than 6 months with shedding of high titer SARS-CoV-2 in an individual with advanced HIV and antiretroviral treatment failure.  More...

Coronaheadsup.com Africa, Co-infection, Coronavirus, D614G, E484K, Health, Infection, K417T, Mutation, N501Y, PCR, Science, South Africa, Testing, Transmission, Treatment, Variants, Y144

UK: Detection of Spike Mutations; D80G, T95I, G142D, △144, N439K, E484K, P681H, I1130V, and D1139H, in B.1.1.482 Lineage (AV.1) Samples from South Yorkshire, UK

“Here we report the discovery of 24 recent B.1.1.482 pango lineage SARS-CoV-2 viruses in South Yorkshire that have acquired approximately 23 additional mutations when compared to the majority of other samples of this lineage.  More...

Coronaheadsup.com AY.1, Coronavirus, E484K, England, Europe, Health, Infection, Mutation, N439K, P681H, Testing, Transmission, UK, Variants

Cameroon: travel-driven emergence and spread of SARS-CoV-2 lineage B.1.620 with multiple VOC-like mutations and deletions in Europe

“In this study we have presented evidence that a SARS-CoV-2 lineage designated B.1.620, first detected in Europe in late February, is associated with Central Africa, where it appears to circulate at very high prevalence, and has been introduced into Europe and the US on multiple occasions.  More...

Coronaheadsup.com Africa, B.1.620, Cameroon, Coronavirus, E484K, Equatorial Guinea, Health, Infection, Mutation, P681H, PCR, Science, Testing, Transmission

NEJM: In two coronavirus vaccine breakthrough cases “examination of the SARS-CoV-2 sequences revealed that both patients were infected with variant viruses” .. “neither sequence precisely fit any known clade”

Examination of the SARS-CoV-2 sequences revealed that both patients were infected with variant viruses.  More...

Coronaheadsup.com America, B.1.526, Coronavirus, D614G, E484K, Health, Infection, Mutation, New York State, P681H, PCR, Science, USA, Vaccine Breakthrough