Preprint: Persistent #coronavirus infection and intra-host evolution in association with advanced HIV infection

“Here we present a case of prolonged infection of greater than 6 months with shedding of high titer SARS-CoV-2 in an individual with advanced HIV and antiretroviral treatment failure. …Through whole genome sequencing at multiple time-points, we demonstrate the early emergence of the E484K substitution associated with escape from neutralizing antibodies, followed by other escape mutations and the N501Y substitution found in most variants of concern.”

Preprint: Persistent SARS-CoV-2 infection and intra-host evolution in association with advanced HIV
infection

 

 

Photo by National Cancer Institute on Unsplash

Peru: 40% of #coronavirus cases in Lima are caused by the P.1 Brazilian variant

Approximately 40% of cases of the new coronavirus in Lima have been due to the P.1 Brazilian variant of this disease, according to a study carried out by the Peruvian National Institute of Health (INS).

This was indicated in a press conference by the Minister of Health, Óscar Ugarte . He added that the advance of this variant that has already passed through Loreto and Huánuco is being determined .

“This INS study is extremely important because it has made it possible to identify, through a sampling throughout Lima, that the main variant that causes COVID-19 today in a percentage of 40% is the Brazilian variant,” he said.

RPP.pe report

 

 

Image by Alex Phillc from Pixabay

USA: 50 cases of #coronavirus variant P.1 found in Barnstaple County, Cape Cod

Genetic sequencing of positive COVID-19 cases in the past week in Barnstable County, Cape Cod, has resulted in the identification of 50 cases of the P.1 virus variant that originated in Brazil, according to the state Department of Public Health. That’s all but seven of the 57 cases of P.1 that have been detected statewide, the DPH said. The state’s first case, announced March 16, was a Barnstable County woman in her 30s.

Cape Cod Times report

 

Image by John French from Pixabay