
Preprint: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2
In this study, we reported the emergence and spread of the novel B.1.621 lineage of SARS-CoV-2, a new VOI with the insertion 146N and several amino acid substitutions in the Spike protein (T95I,Y144T, Y145S, R346K, E484K, N501Y and P681H). Although B.1.621 does not meet all of the VOC classification criteria so far, the set of mutations gathered the Spike protein could confer a synergistic impact on attributes such as reduction of vaccine-induced protection from severe disease, increased transmission and disease severity
Medrxiv preprint: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2
Image by gustavo9917 from Pixabay
** This post was originally published on August 7, 2021 **