Tag: N501Y

Preprint: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2

In this study, we reported the emergence and spread of the novel B.1.621 lineage of SARS-CoV-2, a new VOI with the insertion 146N and several amino acid substitutions in the Spike protein (T95I,Y144T, Y145S, R346K, E484K, N501Y and P681H).  More...

Coronaheadsup.com America, B.1.621, Belgium, Colombia, Coronavirus, E484K, Genome, Infection, Mutation, N501Y, P681H, Science, Testing, Transmission, Vaccine Breakthrough, Y144

Preprint: Persistent coronavirus infection and intra-host evolution in association with advanced HIV infection

“Here we present a case of prolonged infection of greater than 6 months with shedding of high titer SARS-CoV-2 in an individual with advanced HIV and antiretroviral treatment failure.  More...

Coronaheadsup.com Africa, Co-infection, Coronavirus, D614G, E484K, Health, Infection, K417T, Mutation, N501Y, PCR, Science, South Africa, Testing, Transmission, Treatment, Variants, Y144

UK SAGE: Lab studies suggest that the N501Y spike protein mutation increases binding to rat and mouse ACE2 leading to viral replication

A report issued by the UK government’s Scientific Advisory Group for Emergencies (SAGE) found the likelihood that a variant of concern (VOC) that has arisen in humans could infect a rodent and then spread among the animals is high.  More...

Coronaheadsup.com Animals, B.1.1.7, B.1.351, Coronavirus, England, Health, Infection, London, N501Y, Northern Ireland, P.1, Reservoir, Science, Scotland, Testing, Transmission, UK, Wales

USA: 50 cases of coronavirus variant P.1 found in Barnstaple County, Cape Cod

Genetic sequencing of positive COVID-19 cases in the past week in Barnstable County, Cape Cod, has resulted in the identification of 50 cases of the P.1 virus variant that originated in Brazil, according to the state Department of Public Health.  More...

Coronaheadsup.com America, Brazil, Coronavirus, E484K, Health, Infection, K417T, Mutation, N501Y, P.1, Science, Transmission, USA, Variants

France: novel coronavirus SARS-CoV-2 variant derived from Clade 19B with spike substitutions N501Y, L452R, and H655Y – named HMN.19B or Henri Mondor variant

We report a novel severe acute respiratory syndrome coronavirus 2 variant derived from clade 19B (HMN.19B variant or Henri Mondor variant).  More...

Coronaheadsup.com 19B/501Y, Coronavirus, Europe, France, H655Y, Health, HMN.19B Henri Mondor variant, Infection, L452R, Mutation, N501Y, Science, Testing, Transmission, Variants