Nearly 300 Rhode Islanders have tested positive for COVID-19 after being vaccinated against the virus — a total that state public-health officials consider a positive sign of the vaccines’ effectiveness. Three of the state’s 290 post-vaccination positive cases died and 20 were hospitalized, the state Department of Health said Tuesday.
The 290 “breakthrough” infections, as post-vaccine cases are known, came out of 212,060 people who received their final shot 14 days ago, representing about 0.13% of that group.
All three global VoCs (B.1.1.7, B.1.351, and P.1) have now been detected in MA. However, unlike B.1.1.7 and B.1.351, P.1 has shown a rapid rise in frequency in the few weeks following its first detection on March 16th, 2021. Phylogenetic analysis of these 54 P.1 genomes from MA, alongside four additional P.1 genomes from neighbouring states (two from Connecticut (CT) and one each from Maine (ME) and Rhode Island (RI)) and 895 other global P.1 sequences from GISAID, 6 1 suggests at least six introductions of P.1 into MA and at least eight introductions of P.1 into the New England region, likely from both international and domestic sources.
Virological.org preprint – Detection of a large cluster and multiple introductions of the P.1 SARS-CoV-2 Variant of Concern in Massachusetts