Tag: P681H
Preprint: Characterization of the emerging B.1.621 variant of interest of SARS-CoV-2
In this study, we reported the emergence and spread of the novel B.1.621 lineage of SARS-CoV-2, a new VOI with the insertion 146N and several amino acid substitutions in the Spike protein (T95I,Y144T, Y145S, R346K, E484K, N501Y and P681H). More...
Preprint: B.1.617 coronavirus variants show enhanced spike cleavage by furin
“The spike (S) glycoprotein of the SARS-CoV-2 virus that emerged in 2019 contained a suboptimal furin cleavage site at the S1/S2 junction with the sequence 681 PRRAR/S 686. More...
UK: Detection of Spike Mutations; D80G, T95I, G142D, △144, N439K, E484K, P681H, I1130V, and D1139H, in B.1.1.482 Lineage (AV.1) Samples from South Yorkshire, UK
“Here we report the discovery of 24 recent B.1.1.482 pango lineage SARS-CoV-2 viruses in South Yorkshire that have acquired approximately 23 additional mutations when compared to the majority of other samples of this lineage. More...
NEJM “a recombination event between B.1.1.7 and B.1.526” coronavirus variants
Examination of the SARS-CoV-2 sequences revealed that both patients were infected with variant viruses. More...
NEJM: In two coronavirus vaccine breakthrough cases “examination of the SARS-CoV-2 sequences revealed that both patients were infected with variant viruses” .. “neither sequence precisely fit any known clade”
Examination of the SARS-CoV-2 sequences revealed that both patients were infected with variant viruses. More...
Africa: Tanzania/Angola coronavirus variant carries E484K & H655Y mutations
Forbes are carrying an interesting about the recently discovered coronavirus variant found in Tanzania, Africa in travellers arriving from Angola. More...
New SARS-CoV-2 coronavirus lineage that shares mutations with known Variants of Concern (VOC) reported in 20 states across USA
We report a SARS-CoV-2 lineage that shares N501Y, P681H, and other mutations with known variants of concern, such as B.1.1.7. More...
A unique SARS-CoV-2 spike protein P681H strain detected in Israel
Characterization of the Israeli P681H strain: The P681H strain presents as a cluster in a phylogenetic tree of all sequenced samples in Israel, distinct from the B.1.1.7 Pangolin lineage, which also contains the P681H mutation. More...
A novel variant of interest of SARS-CoV-2 with multiple spike mutations detected through travel surveillance [Angola/Tanzania]
“We detected a new VOI in three incoming travelers from Tanzania who were tested together at the airport in mid-February. More...
New coronavirus variant with E484K, N501Y & P681H mutations found in the Philippines, designated PHL-B.1.1.28
Here, we describe the emergence of a new SARS-CoV-2 lineage, mainly from the Central Visayas region of the Philippines. More...