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Preprint: SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis

Coronavirus, Health, Healthcare, Hepatitis, Hospitalization, Moderna, Side Effects, Vaccine

“Here, we report the case of a 52-year-old male, presenting with bimodal episodes of acute hepatitis, each occurring 2-3 weeks after BNT162b2 mRNA vaccination and sought to identify the underlying immune correlates. The patient received first oral budesonide, relapsed, but achieved remission under systemic steroids.”

“COVID19 vaccination can elicit a distinct T cell-dominant immune-mediated hepatitis with a unique pathomechanism associated with vaccination induced antigen-specific tissue-resident immunity requiring systemic immunosuppression.”

Journal of Hepatology article:  SARS-CoV-2 vaccination can elicit a CD8 T-cell dominant hepatitis

 

 

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Photo by Diana Polekhina on Unsplash