Long COVID patients lack naive T and B cells

Nature article: “Patients with long COVID had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection”

“T cell activation (indicated by CD38 and HLA-DR), T cell exhaustion and increases in B cell plasmablasts occur during severe COVID-19”

Full Nature article: Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection