“Gain of Function research hasn’t protected us from this outbreak, hasn’t provided us with any effective treatments or vaccines to save hundreds of thousands of lives lost to CoV2, and if there is even a 0.1% chance GOF research caused the whole thing, that chance is too high”

Asia, China, Coronavirus, Health, Origins

Lab-Made? SARS-CoV-2 Genealogy Through the Lens of Gain-of-Function Research

CoV2 is an obvious chimera (though not nesessarily a lab-made one), which is based on the ancestral bat strain RaTG13, in which the receptor binding motif (RBM) in its spike protein is replaced by the RBM from a pangolin strain, and in addition, a small but very special stretch of 4 amino acids is inserted, which creates a furin cleavage site that, as virologists have previously established, significantly expands the “repertoire” of the virus in terms of whose cells it can penetrate.

From an investigation into the Lab Leak theory for Sars-Cov-2 By Yuri Deigin

 

 

 

 

 

** This post was originally published on April 8, 2021 **