BA.2.75.2 “exhibits more extreme antibody escape than any variant we’ve seen so far”

BA.2.75.2, BA.5, Coronavirus, Evolution, Genome, Health, Infection, Preprint, Research, Revaccination, Treatment, Vaccine, Vaccine Breakthrough

Two preprints have been published over the last few days that give more details about the Omicron BA.2.75.2 sublineage. Both preprints show that BA.2.75.2 could represent a very serious threat to human health in the immediate future.

Ben Murrell, a researcher from the Karolinska Institute in Sweden, has published a long thread on Twitter that we are republishing below. The details are from the first preprint, titled “Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies”

 

Ben Murrell: Full Twitter thread here

Preprint 1: Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies

 

 

In the second preprint, Yunlong Cao has given further details of his work that we first covered in this post. These details are from the second preprint, entitled “Imprinted SARS-CoV-2 humoral immunity induces converging Omicron RBD evolution”.

 

 

 

 

 

 

 

Yunlong Richard Cao: Full Twitter thread here

Preprint 2: Imprinted SARS-CoV-2 humoral immunity induces converging Omicron RBD evolution

 

Good point:

 

 

 

See also: SARS-CoV-2 spike L452R mutation increases Omicron variant fusogenicity and infectivity as well as host glycolysis

 

BA.2.75.2: The “most immune evasive strain we have tested so far”