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Preprint: 40 mutations in a 16-month case of SARS-CoV-2 infection

Coronavirus, Health, Hospitalization, Immunocompromised, Infection, Symptoms, Transmission

Here we describe an approximately 16-month case of SARS-CoV-2 infection in an immunocompromised individual.

“At the earliest timepoint for which sequencing data is available, taken about four months into the infection, we detected 24 mutations that separated the patient’s virus from Wuhan-1. This number gradually increased to 40 mutations by our final sequencing timepoint.”

Preprint: Evolution of a globally unique SARS-CoV-2 Spike E484T monoclonal antibody escape mutation in a persistently infected, immunocompromised individual

 

 

Denmark: patient with coronavirus infection for 333 days that is still ongoing

 

 

Image by Gerd Altmann from Pixabay