SARS-CoV-2 coronavirus spike protein gene variants with N501T and G142D mutation dominated infections in US minks

America, Animals, Canada, Coronavirus, Health, Infection, Mink, Reservoir, Science, Testing, Transmission, USA

We analyzed all animal-derived (977), all Canadian (19,529) and US (173,277) SARS-CoV-2 sequences deposited in GISAID from December 2019 to March 12, 2021, and identified 2 dominant novel variants, the N501T-G142D variant and N501T-G142D-F486L variant, in the US mink-derived SARS-CoV-2 sequences.

These variants were not found in mink-derived SARS-CoV-2 spike protein gene sequences from other countries. The Y453F mutation was not identified in the US and Canadian mink-derive sequences.

Medrxiv preprint





Image by Jan den Ouden from Pixabay

** This post was originally published on April 21, 2021 **