Preprint: Highly divergent lineage of SARS-CoV-2 in deer with potential deer-to-human transmission

America, Animals, Canada, Coronavirus, Deer, Genome, Infection, Testing, Transmission, USA, Zoonosis

We identified a new and highly divergent lineage of SARS-CoV-2. This lineage has 76 consensus mutations including 37 previously associated with non-human animal hosts, 23 of which were not previously reported in deer. There were also mutational signatures of host adaptation under neutral selection. Phylogenetic analysis revealed an epidemiologically linked human case from the same geographic region and sampling period. Together, our findings represent the first evidence of a highly divergent lineage of SARS-CoV-2 in white-tailed deer and of deer-to-human transmission.

Preprint: Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission



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Photo by Anne Zwagers on Unsplash

** This post was originally published on February 26, 2022 **