Robust spike antibody responses and increased reactogenicity in seropositive individuals after a single dose of SARS-CoV-2 mRNA vaccine

Coronavirus, Health, Infection, Science, Treatment, Vaccine

“we show that the antibody response to the first vaccine dose in individuals with pre-existing immunity is equal to or even exceeds the titers found in naïve individuals after the second dose. We also show that the reactogenicity is significantly higher in individuals who have been infected with SARS-CoV-2 in the past. Changing the policy to give these individuals only one dose of vaccine would not negatively impact on their antibody titers, spare them from unnecessary pain and free up many urgently needed vaccine doses.”

https://www.medrxiv.org/content/10.1101/2021.01.29.21250653v1

 

Photo by Hakan Nural on Unsplash

** This post was originally published on February 4, 2021 **