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Denmark: Risk assessment for SARS-CoV-2 Omicron subvariants BA.5, BA.2.12.1 and BA.4

BA.2.12.1, BA.4, BA.5, Coronavirus, Denmark, Europe, Health, Infection, Omicron, Reinfection, Research, Transmission, Vaccine, Vaccine Waning

The sub-variants provisionally amount to 21% (BA.5) and 12.4% (BA.2.12.1) per June 8 2022.

BA.4 currently amounts to 3.7% in week 23 per June 8, and is not considered to show the same growth as BA.5 and BA.2.12.1.

In Denmark, BA.5, BA.2.12.1 and BA.4 have been continuously detected in the sequenced PCR samples since March / April, respectively. BA.5 since 15 April, BA.2.12.1 since 7 April and BA.4 since 2 March. However, in recent weeks there has been a growth in the proportion of BA.5 and BA.2.12.1 among the sequenced samples, which corresponds to a doubling time of more than every week and every other week, respectively, and in week 22, the sub-variants provisionally amount to 21% (BA.5) and 12.4% (BA.2.12.1) per June 8. BA.4 currently amounts to 3.7% in week 23 per. June 8, and is not considered to show the same growth as BA.5 and BA.2.12.1.

There are a total of 726 cases with BA.2.12.1 and 517 cases with BA.5 in Denmark in the period 1 March to 30 May 2022. The pattern in age and geographical distribution is comparable for BA.5 and BA.2.12.1, and also coincides with the general age and geographical distribution. The incidence of reinfections is 14% for BA.5 and 7% for BA.2.12.1 compared to 5% in general throughout the period, but reservations must be made that these are small numbers and that the majority of cases with BA. 5 and BA.2.12.1 are in recent weeks, and there may thus be a greater probability of reinfections due to time alone. Among reinfections for BA.5, there is a proportion (preliminary figures corresponding to 25%), where the previous infection is in the period when omicron has been dominant.

 

Risikovurdering _BA4_BA5_BA2121_09_06_2022 ENGLISH-1

 

 

France: BA.5 at 18% of sequences

 

 

 

Image by İrfan Yiğit from Pixabay