Research: SARS-CoV-2 viral RNAs and spike protein detected in stools of newborn infants

Children, Coronavirus, Health, Healthcare, Infection, PCR, Pregnancy, Research, Reservoir, Testing, Transmission

“Despite negative SARS CoV-2 nasal PCRs from all newborns, viral RNAs and Spike protein were detected in the stool of 11 out of 14 newborns as early as the first day of life and increased over time in six.”

Stool homogenates from all 14 newborns elicited elevated inflammatory IL-6 and IFN-γ from macrophages. Most newborns were clinically well except for one death from gestational autoimmune liver disease and another who developed necrotizing enterocolitis.

These findings suggest in utero transmission of SARS-CoV-2 and possible persistent intestinal viral reservoirs in the newborns.

Nature clinical research: SARS CoV-2 detected in neonatal stool remote from maternal COVID-19 during pregnancy



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** This post was originally published on August 20, 2022 **