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Preprint: Identification of Deltacron recombinants in the United States

America, BA.1, BA.1.1, Coronavirus, Delta, Delta-AY.4, Deltacron, Genome, Infection, Omicron, Recombination, USA

In this report, we describe viruses with recombinant genomes containing signature mutations from Delta and Omicron variants. These genomes are the first evidence for a Delta-Omicron hybrid Spike protein in the United States.

We identify candidate Delta-Omicron recombinant genomes from CDC’s national genomic surveillance and describe efforts to rule out laboratory contamination or sequencing error. We show that these genomes are likely the result of recombination within the Spike gene, containing substitutions common to Delta lineages at the 5’ end and Omicron lineages at the 3’ end .

Preprint: Identification of a Novel SARS-CoV-2 Delta-Omicron Recombinant Virus in the United States

 

 

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