CDC: Addition of SARS-CoV and SARS-CoV-2 chimeric viruses to select agents and toxins list

Coronavirus, Evolution, Recombination, Superspreader events, Transmission, USA

Today, the Centers for Disease Control and Prevention (CDC)’s Division of Select Agents and Toxins published an Interim Final Rule adding SARS-CoV/SARS-CoV-2 chimeric viruses resulting from any deliberate manipulation of SARS-CoV-2 to incorporate nucleic acids coding for SARS-CoV virulence factors to the list of HHS select agents and toxins. In addition, the work to create this chimeric virus is a ‘restricted experiment’ and requires prior approval from CDC before performing the experiment.

HHS/CDC believes that immediate regulatory oversight of these experiments and the resulting chimeric viruses is essential to protect the public from the potential consequences of a release of these viruses.

CDC, 17th November 2021


H/T, the extraordinary Alina Chan:




25th February 2020: “We have contained this. I won’t say [it’s] airtight, but it’s pretty close to airtight,”