Netherlands: BA.1.1/BA.2 recombinant designated XM

A recombinant SARS-CoV-2 variant originally sequenced in the Netherlandshas been designated XM. It’s a combination of the Omicron BA1.1 and BA.2 subvariants.

From Gisaid:

Recombinant between: BA.1.1 & BA.2
Earliest sequence: 2022/2/21 (NL-NH)
Most recent sequence: 2022/3/04 (NL-NH)
Countries circulating: Netherlands (NH)
Likely breakpoint: between 17410 and 19995 (NSP13 or NSP14 or NSP15, ORF1b).
Cov-spectrum query: C15240T, C2470T, A18163G, C19955T, A20055G

Genomes:
hCoV-19/Netherlands/NH_AUMC-004734/2022 EPI_ISL_10925473 2022-03-04
hCoV-19/Netherlands/NH_AUMC-004178/2022 EPI_ISL_10925492 2022-02-21

https://cov-spectrum.org/explore/Netherlands/AllSamples/Past6M/variants?nucMutations=C15240T%2CC2470T%2CA18163G%2CC19955T%2CA20055G

#OmicronUpdates #NewLineageAlerts

XM – New recombinant lineage designated -BA.1.1/BA.2 #Recombinant (Prevalent in Germany, Netherlands and other countries)

Spotted by @JosetteSchoenma

more info: https://t.co/k8UB6ldLWQ pic.twitter.com/8KnsxBsZQa

— Raj Rajnarayanan (@RajlabN) March 31, 2022