Another Deltacron variant has been reported in the UK today, this one combining the Delta variant AY.4 and the Omicron variant BA.1. This is the second Deltacron variant reported in one week. At the time of writing, there appear to be five examples of the recombinant variant.

Likely Break point: Near start of Spike protein

Conserved Spike mutations – T19R /// A67V, Δ69-70, T95I, G142D/Δ143-145, Δ211/L212I, ins214EPE, G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H, T547K, D614G, H655Y, N679K, P681H, A701V, N764K, D796Y, N856K, Q954H, N969K, L981F (/// = proposed break point)

Conserved non-Spike mutations – NSP3 –A488S, P1288L, R1341W, P1469S, A1711V; NSP4 – V167L, T492I; NSP6 – T77A; NSP12 – P323L, G671S; NSP13 – P77L; NSP14 – A394V; NSP16 – L212F; E – T9I; M – D3G, Q19E, A63T; N – P13L, Δ31-33, R203K, G204R

Genomes:
EPI_ISL_9125312
EPI_ISL_9175215
EPI_ISL_9026013
EPI_ISL_9062592
EPI_ISL_9296739

Nextstrain link

We will update this post when we learn more.

First Deltacron report below:

Deltacron lives! Recombination between Delta and Omicron confirmed in the UK