“The natural immune protection that develops after a SARS-CoV-2 infection offers considerably more of a shield against the Delta variant of the pandemic coronavirus than two doses of the Pfizer-BioNTech vaccine, according to a large Israeli study that some scientists wish came with a “Don’t try this at home” label. The newly released data show people who once had a SARS-CoV-2 infection were much less likely than vaccinated people to get Delta, develop symptoms from it, or become hospitalized with serious COVID-19.”
Data for ScienceMag article is from Medrxiv Preprint: Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections
“This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.”
NO, we are ABSOLUTELY NOT recommending you try to get infected with Covid-19!
We’ve had the bug. This BSL4 bioweapon is a devastating beast and you could find yourself in an ICU hospital ward or dead if you try it! Do your best to avoid it all costs.
We are publishing this information so that you can make an informed decision if you have already been infected.
Remember that natural immunity will also fade over time – just think about how many times you have had the flu despite having had it before.
To repeat: Do NOT try to get infected naturally!
A summary table of the studies that have assessed mRNA vaccine effectiveness (VE) for Delta infections, updated with reports from yesterday, overall in line with estimate ~50-60%; *does not pertain* to high VE for hospitalizations or deaths pic.twitter.com/7LxvLoelUI
— Eric Topol (@EricTopol) August 19, 2021
Turkey’s Health Ministry has announced that health workers and priority groups are now eligible to receive a fourth dose of the COVID-19 vaccine as part of the country’s efforts to combat the resurgence of the disease.
The individuals in these groups who have previously had two doses of the Chinese-produced CoronaVac followed by one dose of the Pfizer/BioNTech vaccine as a booster shot will be able to get one more dose of the Pfizer/BioNTech vaccine.
On July 1 the Health Ministry started to offer a third dose of COVID-19 vaccines for people aged 50 and above and health workers who previously had two doses as part of its vaccination drive.
“These results suggest that boosting vaccinated individuals with currently available mRNA vaccines would produce a quantitative increase in plasma neutralizing activity but not the qualitative advantage against variants obtained by vaccinating convalescent individuals.”
Biorxiv preprint: Antibody Evolution after SARS-CoV-2 mRNA Vaccination
Dr Kobi Haviv, Herzog Hospital, Jerusalem: “95% of the severe patients are vaccinated”. “85-90% of the hospitalizations are in fully vaccinated people.” “The effectiveness of the vaccine is waning/fading out”
"95% of the severe patients are vaccinated".
"85-90% of the hospitalizations are in Fully vaccinated people."
"We are opening more and more COVID wards."
"The effectiveness of the vaccine is waning/fading out"
— Ran Israeli (@RanIsraeli) August 5, 2021
The Israeli Health Ministry reported Thursday the efficacy of Pfizer’s coronavirus vaccine in preventing infection has dropped to 39% but the effectiveness in preventing severe illness still remains relatively high.
The report adds the efficacy of the vaccine in preventing serious illness has also dropped and now stands at 91%. The efficacy in preventing hospitalizations among vaccinated now stands at 88%.
5,770 people diagnosed with Covid-19 were fully vaccinated, 495 patients were hospitalized, 334 were hospitalized in a serious condition, and 123 died.
Israel has already begun administering a third dose of Pfizer- BioNTech vaccine to adults with compromised immune systems.
In a separate surprising development, Israel has said it is moving away from the Pfizer vaccine and over to the Moderna vaccine
This Jerusalem Post article gives a credible explanation as to why Israel is reporting vaccine efficacy numbers that are different to those published by recent British studies:
“It is beginning to become clear that vaccine immunity begins to wane after about six months. The Israeli study showed that for people vaccinated more than six months ago, the effectiveness of the vaccine at stopping coronavirus dropped to as low as 16%.”
Blood tests on hundreds of British people revealed that protective antibodies can wane substantially within weeks of second vaccine shots being given.
The UCL Virus Watch study found that antibodies generated by two doses of the Oxford/AstraZeneca and Pfizer/BioNTech vaccines started to wane as early as six weeks after the second shot, in some cases falling more than 50% over 10 weeks.
My colleagues @hillaalroy and @Meir_Marciano have tonight published the data leading the Israeli MoH to suspect that @pfizer vaccine's immunity is waning. In this graph, you can see infections and hospitalizations in the last 3 weeks, normalized. Chances of a January vaccinnated pic.twitter.com/qFNjeGqNXu
— נדב איל Nadav Eyal (@Nadav_Eyal) July 21, 2021
The Covid vaccine may be losing its efficacy in older people, researchers in Israel have warned. The monitoring team at the Hebrew University in Jerusalem reported that about 90 per cent of new confirmed cases in the over-fifties group were people who had been fully vaccinated. “It seems there’s a reduced efficiency of the vaccine, at least for part of the population,” the team said.
People who have recovered from Covid-19 are around 9% of Israel’s population, but they’re less than 1% of current cases. That has led to speculation that recovery from past Covid is more protective against infection from the Delta Variant than vaccination. Known recovered people in Israel are mostly not vaccinated, though some chose to get a single booster dose
“There could be other explanations for this result. The Delta wave is, for now at least, not affecting the communities hardest hit by Israel’s previous Covid waves: Ultra Orthodox Jews and Israeli Arabs. So perhaps recovered people aren’t being exposed to the virus yet.
But I’m not sure that’s enough to explain the sharp difference. From data I was passed last week, recovered people were testing at only 0.1% positivity, compared to more than 1% for vaccinated people.
It’s clear that Delta is spreading in Israel’s vaccinated population. Vaccinated people are getting Delta, and — critically — vaccinated people are giving Delta to other vaccinated people.”
Pfizer Chief Scientific Officer Mikael Dolsten said the recently reported dip in the vaccine’s effectiveness in Israel was mostly due to infections in people who had been vaccinated in January or February. The country’s health ministry said vaccine effectiveness in preventing both infection and symptomatic disease fell to 64% in June.
“The Pfizer vaccine is highly active against the Delta variant,” Dolsten said in an interview. But after six months, he said, “there likely is the risk of reinfection as antibodies, as predicted, wane.”
In a separate report to the one we mentioned earlier where the efficacy of the Pfizer vaccine was estimated to be just 64%, a new study from the Hebrew University reports that the Pfizer vaccine is 70 percent effective against the new ultra-contagious Delta variant. This is compared to an approximately 95% rate of effectivity of the vaccine against earlier strains of COVID. According to the study, the Pfizer-BioNTech vaccine is also less effective at preventing people infected with the Delta variant from developing serious symptoms.
From June 6 – five days after the abolition of all coronavirus restrictions in Israel – until Tuesday, the effectiveness of the [Pfizer] vaccine against corona infection dropped to only 64%. During this period of time there was also a similar decrease in the effectiveness of the vaccine with respect to the onset of symptoms of the disease, although it should be noted that these are only mild symptoms.
Either way, the effectiveness of the vaccine against serious illness or from hospitalization remains quite high. According to the data, between May 2 and June 5, the effectiveness of the vaccine in preventing hospitalization was 98.2%, but fell to 93% between June 6 and July 3 – a decrease of about five percent. A similar decrease was recorded during this time period also with regard to the effectiveness of the vaccine with regard to the development of severe coronavirus disease among vaccinated people. According to the Israeli Health Ministry, 55% of those infected from June 6th were vaccinated.
Israeli Health Ministry: Vaccine down to 64% effectiveness in averting symptomatic COVID
Times of Israel report (in English)
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