Tag: K417T
Preprint: Persistent coronavirus infection and intra-host evolution in association with advanced HIV infection
“Here we present a case of prolonged infection of greater than 6 months with shedding of high titer SARS-CoV-2 in an individual with advanced HIV and antiretroviral treatment failure. More...
USA: 50 cases of coronavirus variant P.1 found in Barnstaple County, Cape Cod
Genetic sequencing of positive COVID-19 cases in the past week in Barnstable County, Cape Cod, has resulted in the identification of 50 cases of the P.1 virus variant that originated in Brazil, according to the state Department of Public Health. More...
First case of the P.1 Brazil coronavirus variant found in Denmark with mutations N501Y, K417T & E484K
Denmark’s SSI: The Technical University of Denmark, DTU, has found a case of the P1 variant, which was originally detected in Brazil. More...
Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil P1 coronavirus
Through genome sequencing of viruses sampled in Manaus between November 2020 and January 2021, we identified the emergence and circulation of a novel SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor. More...
Genomic characterisation of an emergent SARS-CoV-2 lineage in Manaus, Brazil
“We have detected a new variant circulating in December in Manaus, Amazonas state, north Brazil, where very high attack rates have been estimated previously. More...