Israel: Fourth dose of vaccine gives limited protection against Omicron infection

Preliminary results from the study conducted at Sheba Medical Center showed that after receiving the fourth shot, participants developed higher coronavirus antibody levels, but they were only partly effective in preventing Omicron infections.  More...

Long COVID patients lack naive T and B cells

Nature article: “Patients with long COVID had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection”

“T cell activation (indicated by CD38 and HLA-DR), T cell exhaustion and increases in B cell plasmablasts occur during severe COVID-19”

Full Nature article: Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

 

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Long COVID in 2009: Mental Morbidities and Chronic Fatigue in SARS Survivors

From 2009, Long COVID in SARS survivors:   Over 40% of the respondents had active psychiatric illnesses, 40.3% reported a chronic fatigue problem, and 27.1% met the modified 1994 Centers for Disease Control and Prevention criteria for chronic fatigue syndrome.   More...

Global case fatality rate drops to its lowest ever level during the pandemic

Finally, some good news on the Covid front. Whilst the world battles its way through a blizzard of Omicron, the lower death rate for the variant has sent the global case fatality rate tumbling to just 1.86%, the lowest level since the beginning of the pandemic.  More...