Tag: VOC
Japan identifies a B.1.1.28 coronavirus strain with E484K and N501Y mutations from a traveller from the Philippines
The National Institute of Infectious Diseases, Japan, identified a B.1.1.28 strain with E484K and N501Y mutations from a SARS-CoV-2-positive sample collected on February 25, 2020 at a point of entry to Japan from a traveller from the Philippines（virus name : hCoV-19/Japan/IC-0824/2021, GISAID Accession ID: EPI_ISL_1198832) (1). More...
New coronavirus variant under investigation in the UK, B.1.324.1, has key E484K and N501Y mutations
A new variant identified in the UK has been designated a Variant Under Investigation (VUI) by Public Health England. More...
Lancet: Surveillance of coronavirus in Zimbabwe shows dominance of variants of concern – B.1.351 (501Y.V2) and A.23.1
In December, 2020, 95 (89%) of 107 sequenced cases contained mutations of concern, rising to 102 (98%) of 104 in January, 2021. More...
BMJ: B.1.1.7 “in addition to being more transmissible, seems to be more lethal”
Results The mortality hazard ratio associated with infection with VOC-202012/1 compared with infection with previously circulating variants was 1.64 (95% confidence interval 1.32 to 2.04) in patients who tested positive for Covid-19 in the community. More...
UK has sequenced about 45% to 48% of all SARS-CoV-2 genomes in the Gisaid database.
The UK is a world leader in sequencing SARS-CoV-2, the virus that causes COVID-19. More...
SARS-CoV-2 VOC 202012/01 B117 has about twofold replicative advantage and acquires concerning mutations
We have estimated growth rates of expanding mutations acquired by the VOC lineage to find that the L18F substitution in spike has initiated a substrain of high replicative advantage in relation to the remaining VOC substrains. More...
Kent Sars-Cov-2 variant with E484K mutation found in Bristol named VOC 202102/02
A mutated version of the coronavirus variant first detected in Kent has been classified as a cause for “concern” by scientific advisers to the government. More...
SARS-CoV-2 reinfection by the new Variant of Concern (VOC) P.1 in Amazonas, Brazil
“In this study, we report the first documented case of reinfection with the newly emerging P.1 lineage in a 29-years-old individual from Amazonas, a Brazilian state that was severely hit by COVID-19 at the first epidemic wave between March and July, and is currently facing a spiraling surge of deaths since November 2020. More...
NERVTAG: there is a realistic possibility that infection with VOC B117 is associated with an increased risk of death compared to infection with non-VOC viruses
“Several new analyses are however consistent in reporting increased disease severity in people infected with VOC B.1.1.7 compared to people infected with non-VOC virusvariants.” More...
Estimated transmissibility and severity of novel SARS-CoV-2 Variant of Concern 202012/01 in England
“..the increase in transmissibility is likely to lead to a large increase in incidence, with COVID-19 hospitalisations and deaths projected to reach higher levels in 2021 than were observed in 2020, even if regional tiered restrictions implemented before 19 December are maintained”. More...