Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil P1 coronavirus

Through genome sequencing of viruses sampled in Manaus between November 2020 and January 2021, we identified the emergence and circulation of a novel SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor.  More...

Phylogenetic relationship of SARS-CoV-2 sequences from Amazonas with emerging Brazilian variants harboring mutations E484K and N501Y in the Spike protein

Here we report a preliminary genomic analysis of SARS-CoV-2 B.1.1.28 lineage circulating in the Brazilian Amazon region and their evolutionary relationship with emerging and potential emerging SARS-CoV-2 Brazilian variants harboring mutations in the RBD of Spike (S) protein.  More...

South Africa Has Found About 4,000 Covid-19 Reinfections with B.1.351 501Y.V2

South Africa confirms 4,000 reinfections due to B.1.351

The president of the South African Ministerial Advisory Committee on Vaccines, Barry Schoub, reported this Wednesday that some 4,000 reinfections of coronavirus have already been registered in the country due to the mutation of one of its strains.

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