Tag: E484K

Japan identifies a B.1.1.28 coronavirus strain with E484K and N501Y mutations from a traveller from the Philippines

The National Institute of Infectious Diseases, Japan, identified a B.1.1.28 strain with E484K and N501Y mutations from a SARS-CoV-2-positive sample collected on February 25, 2020 at a point of entry to Japan from a traveller from the Philippines（virus name : hCoV-19/Japan/IC-0824/2021, GISAID Accession ID: EPI_ISL_1198832) (1).  More...

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Antibody resistance of coronavirus variants B.1.351 (SA) and B.1.1.7 (UK)

“Findings on B.1.351 [South Africa variant] are more worrisome in that this variant is not only refractory to neutralization by most NTD mAbs but also by multiple individual mAbs to the receptor-binding motif on RBD, largely owing to an E484K mutation.  More...

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New coronavirus variant in Oregon has B.1.1.7 backbone with E484K mutation – “seems to have evolved independently”

The new coronavirus variant that surfaced in Oregon has the same B.1.1.7 backbone, but also a mutation – E484K, or “Eek” – seen in variants of the virus circulating in South Africa, Brazil and New York City.  More...

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