Science Magazine: Covid vaccines may cause Long Covid–like symptoms

In November 2021, in the New England Journal of Medicine, William Murphy, an immunologist at the University of California, Davis proposed that an autoimmune mechanism triggered by the SARS-CoV-2 spike protein might explain both Long Covid symptoms and some rare vaccine side effects.  More...

Long COVID patients lack naive T and B cells

Nature article: “Patients with long COVID had highly activated innate immune cells, lacked naive T and B cells and showed elevated expression of type I IFN (IFN-β) and type III IFN (IFN-λ1) that remained persistently high at 8 months after infection”

“T cell activation (indicated by CD38 and HLA-DR), T cell exhaustion and increases in B cell plasmablasts occur during severe COVID-19”

Full Nature article: Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

 

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Long COVID in 2009: Mental Morbidities and Chronic Fatigue in SARS Survivors

From 2009, Long COVID in SARS survivors:   Over 40% of the respondents had active psychiatric illnesses, 40.3% reported a chronic fatigue problem, and 27.1% met the modified 1994 Centers for Disease Control and Prevention criteria for chronic fatigue syndrome.   More...