12th March 2020 – Boris Johnson: “many more people will lose loved ones to coronavirus” (Guardian).
13th April 2021 – Boris Johnson: “sadly we will see more hospitalisation and deaths” (Guardian)
Among a cohort of 20,714 US children with COVID-19, more than 1 in 10 were hospitalized, of whom 31.1% (756) had severe COVID-19, defined as requiring admission to the intensive care unit (ICU), mechanical ventilation, or comparable treatment. The study found that 2,430 (11.7%) of the 20,714 children who had an emergency department or inpatient encounter were hospitalized with COVID-19.
Discharge data from 869 US medical facilities from Mar 1 to Oct 31, 2020 showed that most hospitalized COVID pediatric patients were girls (52.8%) and 12 to 18 years of age (53.8%); 29.2% had at least one chronic condition. Similar to COVID studies in adult populations, Hispanic and Black populations were overrepresented at 39.3% and 24.4%, respectively. However, when the researchers looked at factors for severe COVID-19, race did not have any significant associations, and neither did insurance type.
The likelihood for severe COVID-19 increased if the patient had at least one chronic condition (adjusted odds ratio [aOR], 3.27; 95% confidence interval [CI], 2.44 to 4.37) or male (aOR, 1.52; 95% CI, 1.26 to 1.83). Likelihood also increased if the child was 2 to 5 or 6 to 11 years of age versus a teenager (aORs, 1.53 for both; 95% CIs, 1.11 to 2.13 and 1.04 to 2.23, respectively).
“Although admission to an intensive care unit for younger children may indicate an abundance of caution by clinicians or facility and administrative requirements rather than disease severity, this finding has important clinical and resource planning implications for facilities and clinicians,” the researchers write. “Understanding factors associated with severe COVID-19 disease among children could help inform prevention and control strategies.”
Twenty out of 30 children (66.6%) assessed between 60 and 120 days after initial COVID-19 had at least one persisting symptom (13 had one or two symptoms, 7 had three or more); 35 of 68 children (27.1%) had at least one symptom 120 days or more after diagnosis (21 had one or two symptoms, 14 had three or more). 29 out of the 68 (42.6%) children assessed >120 days days from diagnosis were still distressed by these symptoms.
More than 200 children in the Czech Republic have been diagnosed with a rare condition that can occur several weeks after Covid-19, known as paediatric multi-system inflammatory syndrome or PIMS-TS. If untreated,it can cause tissue damage, poor function of vital organs or potentially even death.
The PIMS-TS syndrome first appeared in the Czech Republic in the autumn during the second wave of the Covid-19 epidemic. According to the head of the paediatric clinic in Prague’s Motol hospital, Jan Lebl, most doctors had not previously encountered such a medical condition.
Spanish pediatricians have complied the most complete data about ‘multisystem inflammatory syndrome’ MIS-C (aka PIMS) which is a rare consequence of the SARS-CoV-2 virus and causes critical inflammation
Children who, four to six weeks after having been infected with the coronavirus, would fall ill with continuous fever, general inflammation and other symptoms that put their lives at risk – despite having completely recovered from the initial infection.
“They were youngsters aged eight to 14 who were arriving with strong abdominal pains and fever lasting several days,” explains Alberto García-Salido, a pediatrician from the intensive care unit (ICU) at Madrid’s Niño Jesús Hospital. “They didn’t have respiratory symptoms like the adults did.