Category: Preprint
Preprint: SARS-CoV-2 may have originated as an infectious clone assembled in vitro
A new preprint out today finds that SARS-COV-2 has “a synthetic fingerprint unlikely to have evolved from its close relatives.” More...
Chimeric SARS-CoV-2 variant with a mortality rate of 80% *5 Updates*
Boston University scientists undertake a gain of function experiment and create a chimeric recombinant SARS-CoV-2 virus with 80% mortality rate in mice. More...
XBB and three other SARS-CoV-2 strains found to be more antibody-evasive than BQ.1.1 and BA.2.75.2
The speed with which SARS-CoV-2 is now evolving is quite breathtaking – ever-fitter variants are now being uncovered on an almost daily basis. More...
Preprint: Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2
A new preprint on Biorxiv looking at the nuclear translocation of S protein and mRNA in infected cells is attracting a lot of attention online today. More...
Preprint: Reevaluation of antibody-dependent enhancement for SARS-CoV-2 treatments
A new preprint looking at the evidence for antibody-dependent enhancement (ADE) is getting a LOT of attention online – we link to it below so that you can read it for yourself. More...
Preprint: Russian Khosta-2 bat virus resistant to SARS-CoV-2 vaccines
“We found that the spike from virus, Khosta-2, could infect cells similar to human pathogens using the same entry mechanisms, but was resistant to neutralization by serum from individuals who had been vaccinated for SARS-CoV-2.” More...
BA.2.75.2 “exhibits more extreme antibody escape than any variant we’ve seen so far”
Two preprints have been published over the last few days that give more details about the Omicron BA.2.75.2 sublineage. More...
Preprint: White-tailed deer still harbouring Alpha, Gamma and Delta variants in New York
Nine lineages including three major variants of concern; Alpha, Gamma and Delta, were detected in White-tailed deer samples in New York. More...
Preprint: Susceptibility of alpaca, cattle, sheep, horse, goat and rabbit to intranasal infection with SARS-CoV-2
“We report pilot studies to evaluate the susceptibility of common domestic livestock (cattle, sheep, goat, alpaca, rabbit, and horse) to intranasal infection with SARS-CoV-2.” More...
Preprint: Severe organ damage in zebrafish infected with SARS-CoV-2
“Our studies revealed that zebrafish showed inflammatory reaction to SARS-CoV-2 rSpike protein which provoked damage to organs (liver, kidney, ovaries and brain) …and resulted in 78.6% of survival rate in female adults during the first seven days.” More...