mRNA vaccine booster dose antibodies – quantity not quality

“These results suggest that boosting vaccinated individuals with currently available mRNA vaccines would produce a quantitative increase in plasma neutralizing activity but not the qualitative advantage against variants obtained by vaccinating convalescent individuals.”...More...

India: Covaxin and Covishield vaccines invoke 50% fewer antibodies against B.1.617 coronavirus variant

Scientists at the Indian National Institute of Virology (NIV), Pune, have found that both Covaxin and Covishield produce half as many antibodies against the B.1.617 variant of the novel coronavirus as against the ‘original’ B.1 variant....More...

Norway: “there is no other thing than the [AstraZeneca] coronavirus vaccine that can explain that we have received that immune response”

The experts have worked on the basis of a hypothesis that the AstraZeneca vaccines triggered an unexpected immune reaction in the sick health workers, who have triggered the system so that a combination of blood clots and low platelets has been obtained.… ...More...

Antibody resistance of coronavirus variants B.1.351 (SA) and B.1.1.7 (UK)

“Findings on B.1.351 [South Africa variant] are more worrisome in that this variant is not only refractory to neutralization by most NTD mAbs but also by multiple individual mAbs to the receptor-binding motif on RBD, largely owing to an E484K mutation.… ...More...

Denmark was right to cull mink: “SARS-CoV-2 mutations acquired in mink reduce antibody-mediated neutralization”

“These results suggest that antibody responses induced upon infection or certain antibodies used for treatment might offer insufficient protection against SARS-CoV-2 variants from mink.”...More...

Circulating SARS-CoV-2 variants B.1.1.7, 501Y.V2, and P.1 have gained ability to utilize rat and mouse Ace2 and altered in vitro sensitivity to neutralizing antibodies and ACE2-Ig

Here, we first investigated cross-species receptor usage of multiple SARS-CoV-2 variants that emerged during the pandemic.… ...More...