Category: Asia

Asian Coronavirus News

Hong Kong: Link between Covid cases and deaths re-established *4 UPDATES*

Hong Kong may impose a hard lockdown that confines people to their homes, authorities signalled Monday 28th February 2022, with the city’s zero-COVID strategy in tatters and bodies piling up in hospitals.  More...

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Is the global Sars-CoV-2 decline already petering out? *4 UPDATES & 1 PREDICTION*

Is the Omicron decline already petering out? There’s not much to go on yet, a few stutters in the world cases chart, some countries starting to see new surges, but it all looks vaguely familiar.  More...

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WHO: BA.2 to remain classified as Omicron

Based on available data of transmission, severity, reinfection, diagnostics, therapeutics and impacts of vaccines, the group reinforced that the BA.2 sublineage should continue to be considered a variant of concern and that it should remain classified as Omicron.  More...

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Preprint: SARS-CoV-2 infects and replicates in human testes

“The virus remains infective after a long infection period in the testes (viral reservoir)”

This is the first study that shows:
1) the high SARS-CoV-2 tropism to the testis
2) one mode of SARS-CoV-2 entrance in testes
3) SARS-CoV-2 preferred infection and replication in spermatogonia and macrophages
4) that the virus remains infective after a long infection period in the testes (viral reservoir)
5) high levels of angiotensin II and activated mast cells and macrophages are critical players in promoting all testicular alterations
6) the more extended severe condition, the lower the number of surviving germ cells
7) fluctuation in several essential testicular genes
8) that the intratesticular testosterone levels are 30 times reduced in testes of COVID-19 patients
9) the prevalent types of collagen present in SARS-CoV-2 mediated testicular fibrosis
10) the fluctuation of vasoconstrictive peptides in testes of COVID-19 critically ill patients

Medrxiv Preprint: SARS-CoV-2 infects, replicates, elevates angiotensin II and activates immune cells in human testes

 

Sars-CoV-2 – checkmate to the virus in four moves

 

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